Introduction: Epidural anesthesia is a type of neuraxial anesthesia; used for anesthesia of abdominal, pelvic, and lower extremity procedures and, less commonly, thoracic procedures and as a supplement to general anesthesia for thoracic, abdominal, and pelvic procedures and for postoperative analgesia following aforementioned procedures. Aims: A clinical study comparing efficacy of epidural plain Bupivacaine and combination of Bupivacaine plus Fentanyl in abdominal and lower limb surgeries. Materials and Methods: The present clinical study has been carried during 2017-2019,The Study was under taken to compare the efficacy of Bupivacaine and combination of Bupivacaine with fentanyl regarding onset, duration and quality of analgesia when given extraduraly.The study was conducted on 100 adult patients of ASA grade Ι and ΙΙ.