Background: Wilms’ tumour is the commonest renal tumour in children, with unique pathogenesis and histology. Objectives: To determine the different tumour patterns and components, geographical distribution of the patient’s tribes, and the relation of histopathology of the tumour to its clinical presentation and stage. Materials and Methods: We collected the data of 51 Wilms’ tumor patients from January 2006 to December 2010 inclusive from Soba University Hospital, Radio Isotopes Centre Khartoum (RICK) and the National Health Laboratory (NHL) in Khartoum, Sudan. The data was collected from patient’s files using a predesigned questionnaire. Formalin-fixed, paraffin-embedded blocks of processed histopathology specimens were recut, stained and reviewed. SPSS and Microsoft Office Suite 2010 were used in data analysis. Results: The patients’ ages ranged from 0.5 to 10 years with the mean age 3.4 years (SD = 2.1). The male-to-female ratio was 1.6:1.0. Forty two percent of patients were from Western Sudan (n=21). Abdominal mass was the presenting symptom in 50 patients. Duration of symptoms ranged from 3 days to 2 years. Eleven patients (21.6%) presented with metastasis, showing a statistically significant relationship with capsular invasion (P<0.03). Stage III, II, IV and I were diagnosed in 22, 17, 11 and 1 patient, respectively. Triphasic tumours were found in 82.2% of patients, with 61.9% showing mixed elements. Mesenchymal predominance was found in smaller tumours and blastemal predominance in larger tumours (P<0.44). The presence of muscle tissue in the stroma was found to correlate with less advanced stages of the disease (P<0.01). Anaplasia was related to age group 2-6 years (P<0.03), locally infiltrative tumour (P<0.05), and capsular invasion (P<0.02). We found that our results were comparable to other studies conducted in the same region and there is a significant relationship between the histology of the tumour, its size and clinical symptoms.