In 2002 COPD was the fifth leading cause of death. Total deaths from COPD are projected to increase by more than 30% in the next 10 years unless urgent action is taken to reduce the underlying risk factors, especially tobacco use. Estimates show that COPD becomes in 2030 the third leading cause of death worldwide. Sputum cultureand sensitivity was done collecting sputum in sterile containers and were incubated on sheep blood agar, chocolate agar and Mac conkey agar. IgG antibodies against viruses and atypical organisms is done by indirect immunofluorescent assay(IFA) kit.Sensitivityis 94.6% to 100%and specificity is 90% to 100%based on micro-organism.Most of them have smoking history with 82% of Exsmokers and 6% of smokers.Only 12% were non-smokers. Renal failure was seen in 42% of patients. Chest x-ray showed opacities in only 24% of patients.