Introduction: Laparoscopic cholecystectomy is the gold standard treatment for symptomatic gallstones. Generally, most of the surgical procedures may end with complications. One of these complications is surgical site infection (SSI). Materials and Methods: A descriptive study on 250 Patients was conducted by the Department of General Surgery of Narayan Medical College & Hospital, Jamuhar, Bihar. The study duration Was from March 2019 to February 2020. Ethical permission was obtained from the Institutional Ethics Committee and informed written consent forms were obtained from each patient before participation. All the patients were given broad spectrum antibiotics (Ceftriaxone vial 1 g twice daily by intravenous infusion) at the of induction of an aesthesia, in addition with Metronidazole 500 mg three times daily intravenously for 24 hours postoperatively, and for period of five days for those with acute cholecystitis. All data were collected in preformed format and statistical analysis was done.