Background:Major cause of mortality in low-income countries is respiratory infections which are also the third most common cause of death globally. VAP (Ventilator-associated pneumonia) is a vital form of hospital-acquired pneumonia which signifies pneumonia seen in subjects that are mechanically ventilated for a minimum of 48 hours following tracheostomy or tracheal intubation Aims: The present study was conducted to assess the microbiological profile in subjects with Ventilator-associated pneumonia and to assess the bacterial profile in these subjects. The study also assessed the antibiotic susceptibility pattern of bacteria linked with ventilatorassociated pneumonia