Aim: To see if there was a link between sputum eosinophil counts, serum immunoglobulin E (IgE), and asthma severity. Material and methods: It was a prospective observational study conducted in the department of pulmonary medicine at TMMC & RC, Moradabad for one and half year among 62 patients diagnosed as asthma on the basis of spirometry. All the study participants were instructed to cough sputum into sterile plastic containers. Total IgE levels more than 100 IU/mL was taken as abnormal. The degree of reversibility in forced expiratory volume 1 s (FEV1) of 12% and 200 ml from the prebronchodilator value was considered as diagnostic for asthma as per American Thoracic Society standards and GINA 2019 guidelines. Results: Mild, moderate and severe bronchial asthma was revealed in 35.4%, 29.2% and 35.4% of the subjects respectively. S.E.C. and Sr.IgE level increase along with severity of asthma with statistically significant difference. According to Pearson correlation analysis, significant positive correlation was found between S.E.C and Sr.IgE.