Background: Bone marrow is the major hematopoietic organ and is one of the largest organ in human body.1The causes of bone marrow necrosis (BMN) is varied & diverse. Among these cases, hematopoietic malignancy is the commonest. As it is a potential target organ of various disorders, the examination of blood and bone marrow becomes one of the important component for the evaluation of certain disorders.1 It is a rare finding accounting for about 0.3 to 2.2%2,3. Bone marrow necrosis is defined as necrosis of the medullary stroma and myeloid tissues in large areas of the hematopoietic bone marrow (BM), leaving an amorphous eosinophilic background, poorly defined necrotic cells and preserved cortical bone.4