In this paper, DNA computing with Morse code encoding is proposed to bulwark the delicate information within the challenging environment. The plaintext is changed over to DNA sequences utilizing encoding table. Presently, the encoded information is transcript and translated by the RNA arrangements. Translated RNA is stego by the standard genetic code utilizing organic compounds, and the stego DNA is ciphered by Morse code pattern. The designed bio analysis and results show that the hiding capacity is high, and the execution time is less when compared to the current techniques like AES, RSA, DNA based Playfair cipher and Vigenere cipher.