BACKGROUND: Cervical ripening is one of the methods employed for induction of labour. Cervicalripening involves the usage of pharmacological agents or other means to soften, efface or dilate thecervix to increase the likelihood of a vaginal delivery. Induction of labour (IOL) is the process ofinitiatingcontractionsinpregnantpersonswhoarecurrentlynotinlabour,tohelpthemachievevaginaldel ivery within 24 to 48 hours. OBJECTIVE OF THE STUDY: The objective of the study is tocompare the efficacy and safety of two different routes of regimen of misoprostol for cervical ripeningand induction of labour. MATERIALS &METHODS: This prospective comparative study, wasconducted in the Department of Obstetrics and Gynaecology at Adesh Medical College, for a periodfrom may January 2021 to June 2021. We enrolled 100 patients in our study. We divided the patientsintotwogroupsrandomlyintoGroupAandGroupB.GroupAweadministeredmisoprostolvaginal lyandGroupBsublingually.Thedoseusedforboththegroupswas25µg