Background: To ensure long-term implant success, the atrophic maxilla frequently needs bone augmentation before to implant implantation. The application of platelet-rich plasma (PRP) during maxillary augmentation was studied in a prior prospective clinical research. The immediate results revealed no benefit from PRP. The purpose of this study was to assess the long-term effects of PRP on the survival and success of dental implants in the same patient group as the previous study. Materials and methods: In this investigation, 50 patients from the previous study who had been treated for maxillary atrophy with dental implants and autologous bone grafts from the iliac crest were taken into account. 30 patients had treatment using a split-mouth design, where one randomly selected side received additional PRP treatment while the other served as the control side. 20 patients received one-sided treatment and were randomized to either the PRP or the control group. The patients from the prior study had their implants followed up with on average 5 years later. Two distinct success metrics were used to assess the success of the implants. Results: In this study, 30 patients (20 women and 10 males) were examined. The PRP group consisted of 15 patients (10 female, 5 male), whereas the control group consisted of 15 patients (10 female, 5 male). There were 240 implants installed altogether. The PRP group received 100 implants while the control group received 100 implants. The survival rate: 95, while in the control group had a survival rate of 98%. The cumulative likelihood of survival after 5 years was 94% in the PRP group and 98% in the control group, with no discernible difference between the two groups. Albrektson criteria were used to calculate the cumulative success probability, and a higher significant difference was obtained for the control group (p = 0.05). Conclusion: PRP did not have a positive effect on the success and longevity of implants.