Aims and objective: To evaluate the functional and radiological outcome of antegrade Kwire fixation in fracture metacarpal. Material and method: Study includes 25 patients with fracture shaft metacarpal of hand. These patients were treated with antegrade intramedullary K wire fixation between age group (20yr to 60yr). Patients were evaluated as per visual analogue scale (VAS) and disabilities of arm shoulder and hand (DASH) scoring system at 1month, 3 months and 6 months postoperative. Results: All patients treated in this study had clinical and radiological union by the 10th week. Patients had good range of movement at MCP joint following K-wire removal, better DASH score with no joint stiffness and earlier return to work with less complications. Conclusion: Closed K-wire fixation is a good option for treatment of fracture shaft metacarpal. Functional outcome in antegrade intramedullary fixation was attributed to entry from base of metacarpal compared to the conventional retrograde fixation