Herbal medications have been utilised in traditional systems of treatment for thousands of years, including Siddha, Ayurveda, and Unani, among others. Medicinal plants were used extensively by the allopathic system of medicine in order to develop novel molecules for the treatment of difficult disorders. It is commonly recognised that the plant Indigofera aspalathoides, often known as 'Sivanar vembu,' is effective in treating skin problems. Researchers in the fields of phytochemistry and pharmacology have examined it for its anticancerous and antioxidant properties. All of the most recent information on its authenticity, phytochemistry, and pharmacology is covered in detail in this review. An analysis of the plant's phytochemical composition revealed the presence of phenolic compounds, tannin, alkaloids, triterpenes, flavonoids, saponins, and steroids. This medication has undergone extensive testing for its anti-cancerous and anti-oxidant properties. Anti-microbial, hypoglycemic, hepatoprotective, anti-inflammatory, and antiviral activities have all been observed in conjunction with this compound. This plant produces a thailam (oil extracted using a traditional extraction process) that is commonly utilised by Siddha practitioners to treat a variety of diseases. This review focuses on a variety of therapeutic characteristics of the plant that have been scientifically validated, and it provides solid support for the traditional usage of the plant.