As odontogenic infections have multimicrobial etiology like Gram-positive, Gram-negative, facultative anaerobes, and obligate anaerobic bacteria so major proportion of analgesics and antibiotics are prescribed by dentist. The aim of the study was to assess knowledge , practices and awareness of dentist of Kashmir regarding antibiotic prescription and development of resistance .75% of dentist agreed self medication as a prime reason of antibiotic resistance and abuse. As per the survey there was overprescription of antibiotic by the dentist and over the counter use of these medication by patients.