Aims and objectives: To study the role of MR spectroscopy in the evaluation of various ring enhancing lesions in the brain with single and multi-voxel proton MR spectroscopy.Ring enhancing lesions represent an important public health challenge and is a major cause of morbidity and mortality throughout the world. Materials and methods: 100 cases referred to the Department of Radiodiagnosis and Imaging, Government Medical College, Amritsar with clinically suspected brain lesions were evaluated and statistically analyzed.