Introduction: Moringa plant is a plant that is spread throughout the region in Indonesia and has many benefits. Moringa oleifera L. plant is also known as the “miracle of tree” because almost all parts of the plant, from the leaves, bark, seeds, fruit of moringa to the roots are used by humans, especially as traditional medicine. Moringa has been proven effective as antibacterial and anti-inflammatory, for example in toothpaste, mouthwash, and root canal irrigation from chitosan. So this systematic review reviews some of the literature on the potential of moringa plants as antibacterial and antiinflammatory in the oral cavity. Methods: In this systematic review, article searches were conducted on Google Search and Pubmed. Studies published from 2011 to 2020. 104 articles were rated, including 104 articles from electronic databases, 0 from manual search. 96 records were screened, 63 records were excluded, 33 full-text articles were assessed for eligibility and 17 full-text articles were included. Result: There are 8 articles about antibacterial of Moringa oleifera and 10 articles about anti-inflammatory of Moringa oleifera. Conclusion: Based on 18 articles show that chitosan is very potential as a herbal plant that can be antibacterial and anti-inflammatory in the oral cavity.