Hypertension is one of the leading causes of the global burden of disease. Approximately 7.6 million deaths (13-15% of the total) worldwide were attributable to high blood pressure in 200l.The 2003 global report showed that 7 million people die of hypertension each year and approximately 4.5% of serious diseases are caused by it. Written informed consent was obtained from every patient satisfying the inclusion criteria and they were thoroughly explained in writing as well as orally in English/Kannada about the study, methodology and possible risks during the study. In Amlodipine with Atenolol group 86% patients had good quality, and 14% had average physical quality compared to Amlodipine with Enalapril group which had 66.7% in good and 33.3% in average physical quality.In Amlodipine with Atenolol group nearly 88% patients had good quality and 12% had average physical quality compared to Amlodipine with Enalapril group which had 89% in good and 11% in average physical quality.