ABSTRACT: Oral squamous cell carcinoma (OSCC) is the most well-known malignant growth of the head and neck. It represents over 90% of all malignancies which happen in the head and neck region. The high frequency and mortality rate of oral cancer energizing continuation of exploration on finding new indicative diagnostic tools or markers for it. Oral squamous cell carcinoma (OSCC) is the 6th most common threat in the world. It is brought about by an assortment of elements, among which, oxidants, the results of typical digestion, rank high as a significant culprit in the development of the disease.