Online ISSN: 2515-8260

Author : Brundha, M.P.


Kameswari. S; M.P. Brundha; D. Ezhilarasan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 1174-1181

Coronavirus which is an irresistible sickness was spread overall pandemic. First events of obscure etiology in Wuhan, China. This distinguished a novel coronavirus now named as a SARS COV 2. It is secured by fat protein which is a solitary abandoned RNA genome. The infections are round or pleomorphic with wrapped particles.SARS-COV incites a huge scope starting in China and the new infection is by all accounts infectious and the COVs have become the significant pathogens of developing respiratory maladies. The indications of the beginning periods of the infection are vague. The death rates for cases all around stay between 1% to 2%. Rapid duplication of infections is additionally an entangled factor in identifying the ailment. Consequently the recognition of this sickness can be distinguished by different strategies like RT-PCR (Real time Polymerase Chain Reaction), CT (Computed Tomography) and so forth… RT-PCR is one among them. Detection of infection by RT-PCR in clinical examples offers the alternative of conclusion in the beginning periods of the ailment and its application incorporates genotyping, mutation detection. RT-PCR techniques during the initial hardly any long periods of ailment have been low and much better affectability is after day 6 of the ailment. RT- PCR technique which is found to be a standard method for diagnosing the positive cases. This helps in finding true negativity and rule out the serological positive cases. Thus, this review at the advantages and disadvantages of RT- PCR in COVID 19.


N. Naveenaa; Leslie Rani; M.P. Brundha

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 324-333

The facemask is a personal protective equipment which is used to prevent the droplet or aerosol spread. Due to the pandemic spread like SARS, COVID-19 the mask is recommended to be worn by all the people to prevent the infection. It is one of the non-pharmaceutical ways of prevention, it helps in controlling the spread but not in complete eradication of the disease.This is a widely used way of prevention, which is cheap, non-invasive and has capacity to reduce the mortality rate due to respiratory infection. The major problem associated with these equipment are, they are commonly misused and they go out of stock even before the health care sector receives these equipment. So proper selection of masks is required to prevent the infection and also to reduce the demand of masks in the health sector. The aim of this review is to understand the importance of masks and needs of the personal protective equipment during the onset of any pandemic conditions. A systematic search strategy was done and the articles were found using keywords. Literature was taken from databases like PubMed and Google Scholar. The articles which discussed face masks were included and other articles which had the different types, advantages and disadvantages were also included. The review summarises the needs and the urge to use a face mask at the onset of pandemic condition. Selection of proper mask is emphasised to reduce the demand of masks.