Online ISSN: 2515-8260

Author : Girija, A.S.Smiline


OBESITY AS A MAJOR RISK FACTOR IN N- COV DISEASE

J. Dhivyadharshini; A.S.Smiline Girija; Jayalakshmi Somasundaram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 367-375

The review gives an overview on the relation between obesity and n-CoV disease. A review has been done to understand the correlation of obesity with the n-CoV disease by retrieving a maximum of related articles from various search engines like PubMed, Google Scholar, MeSH, Core, Cochrane, bioRxiv, Semantic scholar and so on published from 2000 to 2020 (till date). Obesity is associated with SARS- CoV-2 which enhances inflammatory response in obese people compared to actual standard BMIs. Obesity is often specifically related to producing inflammation by triggering a cytokine storm in the lungs, which raises the likelihood of ARDS, thereby requiring respiratory assistance for the main issue. Obesity can hinder breathing by hampering the excursion of the diaphragm, inhibit immune responses to critical infection, it is pro-inflammatory and triggers diabetes and even oxidizing tension to worsen cardiovascular activity. This study indicates that obese people through respiratory viruses COVID19 are more likely to be hospitalized comparatively. The implementation of novel ideas on obesity control of ailments will certainly bring about a massive change. Constraining less dependence on recent literature in this area and also upgrading numerous research to increase consciousness among the general public so that they may take measures not to be vulnerable to COVID 19. The current research has shown a strong incidence of obesity in patients participating in medical treatment with SARS-CoV-2. Obesity can be hazard factored to SARS-CoV-2 severity which needs increased attention in susceptible individuals to take preventive measures.

ROLE OF TASK FORCE COMMITTEE IN HOSPITAL INFECTION CONTROL DURING EPIDEMICS AND PANDEMICS

Nirubama.K .; A.S.Smiline Girija; Ezhilarasan D

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 2021-2029

Pandemics are defined as large- scale outbreaks that can greatly increase mortality and morbidity over a wide geographic area and cause significant economic, political and social disruption due to spread of infectious disease. Risk of pandemic and epidemic conditions have occurred throughout history and appear to be increasing in frequency, particularly because of the increasing emergence of viral disease from animals. Other associated risk factors include older age, longer hospital stays, immunosuppression, frequent encounters with healthcare facilities, mechanical ventilatory support, multiple underlying chronic illnesses, recent invasive procedures, indwelling devices and being in a critical care unit. Management of acute infections transmitted to susceptible patients via cross infections and emergence of antimicrobial- resistant pathogens need attention in a hospital set-up. Task forces committee are organisations of small groups of resources and people brought together to establish a specific objective, to complete the expectation that the group will disband when the objective has been completed. The task force committee is actively involved in resolving issues on hospital acquired infection during pandemic and epidemic outbreak of disease and this review underpins the same.