Online ISSN: 2515-8260

Author : Arun, Dr Murugaiyan


EVALUATING THE INCIDENCE OF CONSANGUINEOUS MARRIAGES IN PARENTS OF PATIENTS PRESENTING WITH CLEFT PALATE

Dr Sneha Krishnan; Dr. Senthilnathan Periasamy; Dr Murugaiyan Arun

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 936-944

This study is aimed to determine and assess the incidence of consanguineous marriages in parents of patients presenting with cleft palate. This retrospective study involved 48 patients who reported to the Outpatient Dental Department of Cleft and Craniofacial Centre of Saveetha Dental College, Chennai between the year June 2019-March 2020. Parameters such as age, gender, history of consanguineous marriages and presence of other cleft were evaluated and assessed by a single examiner and reviewed by 2 independent investigators. In this study, we observed that the incidence of consanguineous marriages in parents presenting with cleft palate was 18.75%. There also seemed to be a slight female predilection of cleft palate patients with a history of consanguinity (55.55%) as compared to males(44.4%). Within the limits of this study, the consanguinity is associated with cleft palate, the incidence usually being the least among isolated cleft palate patients.

EPIDEMIOLOGIC EVALUATION OF DIFFERENT PHARMACOTHERAPEUTIC TREATMENT MODALITIES FOR MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS

Dr Swetha Bhat; Dr Senthilnathan Periasamy; Dr Murugaiyan Arun

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 927-935

senthilnathan@saveetha.com
3arunm.sdc@saveetha.com
ABSTRACT
The purpose of this study was to highlight various pharmacotherapeutic treatment modalities and to
compile them to assist in early intervention and management of Oral Submucous Fibrosis
This study was conducted on 92 patients who reported to the Department of Oral Surgery and Oral
Medicine, Saveetha Dental College, Chennai. They were clinically diagnosed with oral submucous with
standard data grading and were given a combination of treatments currently available. Out of 92 cases,
85(92.4%) were males and 7(7.6%) were females which showed a male predominance with a ratio of 12:1
in the prevalence of Oral Submucous Fibrosis. The age group affected the most was 35-50 years (54.28%).
Oral systemic antioxidants was prescribed to 54% of the patients and was the most frequently used
treatment modality in the pharmacotherapeutic management of Oral Submucous Fibrosis. Management of
Oral Submucous Fibrosis has been the subject of controversy ever since it was first stated in 1952. This
study attempts to compile the available treatment and its current status to assist early intervention of the
disease.