Online ISSN: 2515-8260

Author : Ashurova, Dilfuza


FORECASTING EPILEPSY RISK IN CHILDREN BORN FROM PARENTS WITH EPILEPSY

Muslima Mambetkarimova; Dilfuza Ashurova; Yakutkhon Madjidova; Nadira Zakirova; Sherali Ergashev

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2375-2381

This article details the condition of newborn babies from mothers with epilepsy.
The frequency and nature of epilepsy in children born to mothers with epilepsy are
described. Risk factors for the development of epilepsy in children born to mothers with
epilepsy were determined.

FEATURES OF DIAGNOSTICS OF CARDIOVASCULAR AUTONOMOUS NEUROPATHY OF CHILDREN WITH DIABETES MELLITUS TYPE 1

Dilfuza Ashurova; Azizakhon Sadirkhodjaeva; Malika Khaldarbekova; Zukhra , Shermatova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2382-2392

Abstract. The presence of cardiovascular autonomic neuropathy (CAN) significantly
worsens the prognosis and course of the underlying disease. So in patients with diabetes
mellitus (DM) and CAN, the mortality rate for 5 years is five times higher compared to
patients without this complication. Due to the fact that CAN is closely associated with
cardiovascular pathology, many authors consider CAN as a significant factor in
cardiovascular risk. Purpose. To establish clinical, functional and metabolic changes in
diabetic autonomic cardiovascular neuropathy in children with type 1 diabetes. Materials and
methods research. The total number of patients studied by us was 114 children with type 1
diabetes mellitus aged 4 to 18 years. We conducted laboratory and instrumental research
methods. Laboratory methods: general clinical research (general analysis of blood and urine,
studies of blood sugar), biochemical methods (total blood protein, bilirubin, cholesterol,
triglycerides, creatinine, urea, electrolytes, glycated hemoglobin), 24-hour heart rate
monitoring with circadian index estimation was used and parameters of time and frequency
analysis of heart rate variability. Conclusion diabetic autonomic cardiovascular neuropathy in
children with type 1 diabetes is characterized by the development of tachyarrhythmic rhythm
disturbances, as well as the formation of rigidity of the heart rhythm and a decrease in the
sensitivity of the sinus node to parasympathetic influences according to a temporary analysis
of daily monitoring of heart rhythm.