Online ISSN: 2515-8260

Author : Aliev, Mansur A.


Endolumbal Nootropic-Ozone Therapy In Complex Treatment Of Patients With Complicated Spinal Injury In Acute Period

Shavkiddin S. Yuldashev; Abdurakhmon M. Mamadaliev; Mansur A. Aliev

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 1571-1576

Abnormal spinal trauma is the most severe damage to the human musculoskeletal system and is found in the 2.3 -4.7% of cases [3, 7, 8]. The lethality of these injuries is up to 25-30% [7, 9, 10], and disability when it reaches up to 86-94% [(2, 7, 8]. In much of the results of treatment depend on the quality of medical aid in acute period of complicated spinal injuries in such cases, the purpose of early and effective treatment of these patients is not only the restoration of the basic function of the spine, but also the development of mechanisms of compensation broken spinal cord functions. Therefore, timely and efficiently provided medical care in specialized institutions significantly improves outcomes of injuries and enhances the quality of life of the victims.
In the last few years to treat complicated injuries of the spine, along with surgical method uses different medications that can help improve metabolism and blood circulation, reduce edema and medications for the injured area of the spinal cord.
So far, have been widely used corticosteroid medications (dexamethasone and methylprednisolone) in acute period of injury. Use of steroid hormones improves metabolism in acute period of spinal cord injury. Corticosteroids also provide stabilizing membranes, reduces edema, "clean" acid radicals, reduce metabolism products contribute to cerebrospinal fluid diffusion of oxygen into the fabric. But the drugs have significant side effects, as well as a number of reasons.
Now continue to search for drugs and methods aimed at correlation metabolic violations in the spinal cord, resulting in hypoxia and to improve treatment outcomes.

To Questions Of Surgical Tactics In Damagesof The Thoracic And Lumbar Parts Of The Spine

Shavkiddin S. Yuldashev; Abdurakhmon M. Mamadaliev; Mansur A. Aliev

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 1559-1570

In the overall structure of spinal injuries in adults vertebro-spinal injury ranges from 2.2% to 20.6% [2,5,7,8,10,12,22]. When fractures of the spine are complicated by neurological disorders, most commonly lower thoracic and lumbar vertebrae - 39.2% and 48.5% are injured respectively [2,4,12,15].
According to various authors, the greatest proportion of spinal injuries is accounted for cervical - 30,0-40,0% of cases, followed by lumbosacral - 25,0-45,0%, thoracic - 15,0-25,0% and multilevel spinal injuries - about 5% [3,4,5,7,12,13,15,16,22,24,26].

Research Of Changes Of Essential Elements Composition In The Cerebrospinal Fluid In Patients With Outcomes Of Traumatic Brain Injury Before And After Endolumbar Ozonotherapy

Mansur A. Aliev; Abdurakhmon M. Mamadaliev; Saodat A. Mamadalieva

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 2529-2539

The aim of this research is to investigate the essential elements composition in the cerebrospinal fluid of patients with various outcomes of traumatic brain injury before and after complex treatment with the use of endolumbar and intracystal introduction of ozone and pyracetam in dynamics. Thus, it may be noted positive changes in the metabolism of macro- and microelements in the cerebrospinal fluid of patients