Author : Abdullah Salah Alhasan, Roaa Tareq Hammad , Wajeeh Youns Al-Ani,
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 11, Pages 977-983
Alopecia areata is an autoimmune disease that causes hair loss, and alopecia areata is characterized by patchy hair loss, which includes the scalp and other areas of the head, including eyelashes, beard and entire body hair, which may also be affected. A patient with alopecia areata notes the sudden appearance of a circular patch of hair loss, which may lead to baldness of the entire scalp and is called (Alopecia areata totalis) or loss of full body hair called (Alopecia areata universals).(Finner,2011) The etiopathogenesis of the disease is still unclear, but the role of autoimmunity is strongly suggested. AA is commonly associated with Thyroid disorders; the most frequent among them is autoimmune thyroid disorders. (Kyriakis et al.,2009), (Seyrafi et al., 2005) The aim of our study To determine whether Alopecia Areata (AA) is associated with some hormone such as : Thyroid hormones ( T3, T4 and TSH ). The study included 72 cases with age ranging from (10-50 years) ; (Group A) 42 patients with AA (27 male and 15 female) and (Group B) 30 healthy volunteers ( 7 male and 23 female ) were selected as a control group. All samples were obtained from Dermatology outpatient clinic, Al-Ramadi Hospital, AlAnbar Governorate, Iraq. during the period from December 2019 to march 2020. Every case and control were subjected to history taking, dermatological examination and complete general Venous blood samples were taken from controls and patients after taking their agreement for measurement of some hormones such ; Thyroid Hormones (TSH, T3, T4). We found statistically significant differences between patients and controls regarding Thyroid Hormones levels of TSH, T3 and T4.