Online ISSN: 2515-8260

Author : Acharya, Panchanan Sahoo, Ritesh


Clinical evaluation between Systolic and Diastolic Heart failure

Panchanan Sahoo, Ritesh Acharya

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 636-641

Objectives: Diastolic heart failure (DHF) and Systolic heart failure (SHF) are two
clinical subtypes of the Chronic Heart Failure (CHF) syndrome that is most frequently
seen in clinical practise. SHF and DHF are the two most common clinical subgroups of
Chronic Heart Failure syndrome. To assess the frequencies of CHF and the systolic
dysfunction (SD) and diastolic dysfunction (DD) in the community. To also ascertain
whether DD helps in predicting all-cause mortality.
Study design and sample: This cross-sectional study of 242 participants who have been
selected randomly will be conducted in the state of Bhubaneshwar, India. The inclusive
criteria of the sample are that the age groups must be 45 years or older. This study took
place between June 2020 to July 2021.
Results: Validated CHF was found in 2.2 percent of the participants, with 44 percent of
participants with an EF greater than 50%. 20.8 percent of participants had mild
diastolic disfunction, 6.6 percent had moderate DD, and 0.7 percent had severe DD.
There was a 6.0 percent occurrence of any SD, with 2.0 percent having severe or
moderate SD. People with SD or DD had considerably higher rates of CHF than those
participants with normal cardiac function. Even among individuals with severe or
moderate DD or SD, however, only around half had heard of CHF. Mild DD, severe or
moderate DD, and severe or moderate SD were predictive of mortality across
multivariate analysis, adjusted for sex, EF and age.
Conclusion: SD is present among people who do not have recognised CHF. DD is
common and is not accompanied by CHF. It is associated with an elevation in mortality.

A Community-based Study on the impact of Obesity and Overweight on Left Ventricular Diastolic Function in an Elderly Cohort

Panchanan Sahoo, Ritesh Acharya

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 630-635

Objective: Left Ventricular diastolic dysfunction (LVDD) is an asymptomatic disease
linked to eventual heart failure. Obesity and overweight are not known to be
independently linked to LVDD. The objective is to adjudicate whether increased body
size has an independent influence on LVDD.
Study design and sample: For this study, a total of 495 subjects were selected. LV
diastolic function was estimated using both traditional and tissue-Doppler imaging.
Peak early and late trans-mitral diastolic flow velocities (E, A) and early diastolic mitral
annulus velocity (E′) were utilized to calculate E/A and E/E′. The individuals were
categorised into three groups: overweight (BMI 25.0–29.9), normal weight (BMI 25.0),
and obesity (BMI 30).
Results: BMI was independently linked with greater E, A, and E/E′, an indication of LV
filling pressure, in multivariate models (all p<0.01). Overweight and obese participants
demonstrated lower E′ (both p<0.01) and greater E/E′ (both p<0.01) than respondents
with normal weight. Obese participants had a lower E/A than normal weight
respondents (p<0.01). When contrasted with normal weight people, the perils of
diastolic dysfunction were considerably greater among overweight and obese people.
Conclusion: Irrespective of LV mass or other risk variables, having an elevated BMI
was connected to poor LV diastolic performance. Both overweight and obese patients
have higher chances of LVDD, which may explain some of the heart failure associated
risks with both conditions