European Journal of Molecular & Clinical Medicine

Background:An infection of the natal cleft and sacrococcygeal area that affects mostly teenagers and young adults. The biggest disadvantage is wound healing. The lack of a superior surgical procedure is due to the numerous proposed surgical techniques. The study will describe the modified Bascom procedure and its effects in individuals with pilonidal illness. Objectives:The purpose of this study is to evaluate the modified Bascom procedure and its results in patients with pilonidal disease.
Materials and Methods: From October 2020 to May 2021, patients presenting to JSS Hospital, Mysuru with pilonidal sinus were studied prospectively. Patient selection is based on a thorough history, physical examination, and basic pre-operative examinations. Thirty cases receive modified Bascom. The patient's rate of cure, postoperative complications, and recurrence are observed.
Results: In this study of 20 patients, there was a 9:1 male preponderance. 20.46 + 9.42yrs mean age of presentation Pilonidal sinus is widespread in persons who sit for long periods of time as drivers, students, etc. Acute pilonidal sinus to chronic discharge sinus. These patients' hospital stay, healing time, wound infection, wound dehiscence, and recurrence were evaluated, and the results were favourable. Our patients had wound infection and dehiscence, although the rate of recurrence and complications, hospital stay (4.42 + 1.24 days), and wound healing time (19.6 + 1.22 days) was low compared to previous operations.
Conclusion: Study demonstrates pilonidal illness affects guys in their 30s and 40s. Occupation and local anatomical factors play a role in illness development. Pilonidal disease is diagnosed clinically. There are several options for treating pilonidal disease. The primary closure is the most effective, with low recurrence rates, less problems, and faster healing

Background:Intra-abdominal infections have been treated with various antibiotic regimens. These infections have been treated with single-agent and combination treatments. But no one therapy has been proven superior. The study's main goal is to examine the bacterial patterns in peritoneal fluid from surgical peritonitis patients and assess their antibiotic sensitivity and resistance.
Materials and Methods: It is a cross sectional observation research conducted in January 2020 to May 2021 which was conducted in JSS Hospital Mysuru. Analyzed data was in rates, proportions, and percentages. The sample includes 100 cases of secondary peritonitis caused by hollow viscus perforation, where preoperative peritoneal fluid samples were analysed for bacterial culture and sensitivity.
Results: Out of 100 samples, 50 had bacterial growth. The most common bacteria were E. coli. These were Acinobacter (6%), Candida (4%), Citrobacter (1%), Klebsiella (11%) and Serratia (2%). (4 percent). 77.5 percent of E. coli were sensitive to Ceftriaxone, 75% to Piperacillin-tazobactam, and 99.1 percent to Meropenem. In 40% of cases, E.coli was multidrug resistant. Most Klebsiellapneumoniae were responsive to ceftriaxone, piperacillin-tazobactam, and meropenem. Ciprofloxacin, Ceftriaxone, and Meropenem were all sensitive to Proteus mirabilis. 25.2 percent of cases were multidrug resistant bacteria.
Conclusion: The results of this investigation identify the organisms usually isolated from peritoneal fluid, their susceptibility and resistance to broad spectrum antibiotics. It shows the common gramme negative isolates and the current antibiotic resistance concern in these individuals. The most common microorganism found in gastrointestinal perforations is Escherichia coli. In most cases, numerous gramme negative bacilli develop polymicrobially. Antibiotic-resistant microorganisms, notably multidrug resistant Escherichia coli, are increasing in number. Third generation cephalosporins are becoming more resistant. In multidrug resistant organisms, Meropenem and Tigecycline seem to be the best options.