Online ISSN: 2515-8260

Author : A, Kumaresan


Effect Of Open And Closed Kinematic Chain Ankle Exercises On Improving Proprioception And Balance A Systematic Review

Thanthoni S; Pavithra S; Prathap Suganthirababu; Kumaresan A; Vignesh Srinivasan; Priyadharshini Kumar; Divyalaxmi P; Aravind Ganesh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 307-315

Background: The purpose of this study was to find out the effect of open and closed kinematic chain ankle exercise on improving balance and proprioception.
Aim:This study aimed to evaluate the effectiveness of open and closed kinematic chain ankle exercises on improving proprioception and balance. The study emphasizes the effect of balance, proprioception.
Methods:The objective of the study was approached with Systematic review study design and database used to look for articles include Cochrane Library Trials, PubMed Central, PEDro, Rehab data, Research Gate, and SAGE Journals. We collected 134 articles between the year1989to 2020 and analysed stratergiocally using PRISMA guideline and 3 were selected for analysis based on its relevance with selection procedures.
Result:The studies included investigated the prevalence of reduced balance, proprioception,open and closed kinematic exercises .
Conclusion:The study showed that there mightis an marginal effect of open and closed kinematic chain ankle exercise on improving proprioception, balance and further studies are needed to prove its significance.

Qualitative and Quantitative Dermatoglyphics and the Estrogen Exposure in Breast Cancer Risk: an Epigenetic Context.

Lavanya Prathap; Prathap Suganthirababu; Kumaresan A; Vignesh Srinivasan; Jagatheesan Alagesan

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 480-490

Background – The lastingness of dermatoglyphics suggest epidermal ridges as a bio-signature for studying the epigenetic insults in the prenatal period. Approaching the preventive measures in epigenetic viewpoint aid to reduce the incidence of carcinoma.  Objective – To inquire the association of qualitative and quantitative dermatoglyphics and the estrogen exposure in spotting out breast cancer risk in an epigenetic context. Materials and Methods – We performed the study among 150 females in three groups. The outcome of dermatoglyphic variables includes six or more whorls, Mean finger ridge count, A- B Subtotal ridge count, ATD angle and pattern intensity index. The variables of reproductive and genetic factors are increased menstrual age, Nulliparity, First Full Term Pregnancy >30yrs, and Positive Family History. The statistical procedure used are odds ratio and the level of significance using P- value. Results - Increased menstrual age is significantly associated with six and more whorls (P<0.0001), Mean finger ridge count (P<0.04), A-B Ridge count (P<0.0001), ATD angle (P<0.0001), Pattern intensity index (<0.0001). Nulliparity is significantly associated with the ridge count (P<0.0001), ATD angle (P<0.001), full term pregnancy >30yrs is associated significantly with A-B ridge count (P<0.01), ATD angle (P<0.02), pattern intensity index (P<0.05).Positive Family History is associated significantly with all the variables. Conclusion: To encapsulate six or more whorls are associated with high frequency with positive family history, Mean finger ridge count, and pattern intensity index is related in high frequency with menstrual age and ATD angle is linked in high frequency with nulliparity when compared with other reproductive factors.

Efficacy of self-monitoring virtual feedback exercises for upper motor neuron facial palsy. A double blinded randomized control study.

Vignesh Srinivasan; Nithiyah Maruthey; Prathap Suganthirababu; Kumaresan A; Surya Vishnuram; Aravind Ganesh; Nivya Sebastian

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 471-479

Purpose:
Upper Motor Neuron Facial Palsy is common in those who have had a stroke. Electrical stimulation and other available therapeutic options for UMN facial palsy have been the subject of several research papers. The purpose of this study is to see how effective facial retraining exercise using self-monitoring virtual feedback via a mobile application  for treating UMN facial palsy.
Materials and Method:
An experiment was carried out with the help of 82 volunteers. Based on the selection criteria, all of the participants were separated into experimental and control groupsThe experimental group was given electrical stimulation and face retraining exercises with self-monitoring virtual
feedback via an android application, whereas the control group was given electrical stimulation and conventional exercises.House-Brackmann facial grading score was measured pre and post to the intervention by a blinded assessor who was unaware about group allotment.

Sensory nerve conduction velocity changes in low level laser therapy irradiated diabetic neuropathy induced wistar rats

Prathap Suganthirababu; Lavanya Prathap; Kumaresan A; Vignesh Srinivasan; Jagatheesan Alagesan; Praveenkumar Kandakurti

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 659-673

Background: Management of Diabetic neuropathy with physiotherapy is very limited and extensive research has to be done to address this problem conservatively in a physiotherapy perspective. The aim of the study is to analyze the effect of various dosage of low level laser irradiation on sensory nerve conduction velocity (SNCV) of experimentally induced diabetic neuropathy in wistar rats. Materials and Methods: We performed a randomized controlled trial using simple random sampling method in a CPCSEA Approved, Biomedical Research Unit & Laboratory Animal Centre, Chennai, India. The study carried out in two phases, in the phase I the selected experimental rats are treated with single dose on Alloxon 150mg/kg body weight after 12 hours of fasting. In the Phase II the samples with confirmed neuropathic status were divided into seven groups (six rats in each group) and irradiated with low level laser therapy with various dosages Results: The SNCV result analysis within the groups showed that laser dosage of 3,4j/cm2 are having more sensory regenerative effect as compared with 5-8j/cm2 dose and control group also did not show significant effect. The findings of the present study suggests nerve regeneration through nerve conduction velocity reports. Conclusion: It is evident from the results that an increase in nerve conduction velocity with selective dosages of laser proves that laser has neuroregenerative effects and by analyzing the results it can be concluded that low level laser of 3&4j/cm2 is found to be effective in regeneration of SNCV of experimentally induced diabetic neuropathy as compared with control group and with the dosage of higher energy with 5-8j/cm2.

Factors Influencing Physiotherapy graduates in Choosing Neurological Physiotherapy for Postgraduation in their Professional Career: A Survey Study

Rajashree P; Prathap Suganthirababu; Kumaresan A; Vignesh Srinivasan; Divyalaxmi P; Lavanya Prathap

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 527-532

Background: Factors influencing physiotherapy students in choosing neurological physiotherapy as a career.Objective: The study aimed to identify the factors influencing physiotherapy students in choosing neurological physiotherapy as a career.Methods: The survey study was done on the year 2021 at saveetha college of physiotherapy and other physiotherapy colleges in Chennai. A questionnaire comprising of 16 questions, was administered for neurological physiotherapy students. Students were asked questions pertaining to the importance of four central motives productive, knowledge, social, and personal background for selecting neurological physiotherapy as a career and Likert scale was used to measure the outcomes.  Results: A total of 138 physiotherapy students out of 120 were participated in the survey. The results show that the top four factors, which influenced students to choose neurological physiotherapy as a career and the “productive” factor topped the list.

Fluctuating Asymmetry of Hand Dermatoglyphics in Female Breast Cancer Population

Lavanya Prathap; Prathap Suganthirababu; Kumaresan A; Vignesh Srinivasan; Aravind Ganesh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 500-507

Background: Breast cancer being a common cancer in women among reproductive age, effective screening criteria should be in practice to keep apart the high risk population for breast cancer and thereby prevention of the disease..  The present study identifies the FA of digital and palmar dermatoglyphic variables specific for breast cancer, which can be utilized to set apart the population at risk, take preventive and early therapeutic measures. Methods: The participants are grouped in to 50 each based on selection criteria. Data collected in the form of digital photographic images of the digits and palm of the right and left hand and the variables are analyzed visually with assistance of computer. The Student t’ test is applied to examine the quantitative variables and to measure the FA between dermal ridges of the right and left hand. Results and Conclusion: The typical dermatoglyphic variables that can be utilized to insulate the high risk population includes FA Thumb, FA Ring finger and FA A-B ridge count. The overall observation of the results obtained from the study demonstrated a substantial divergence in the fluctuating asymmetry of dermal ridge patterns of healthy participants from the high risk and breast cancer group and the patterns followed in high risk and breast cancer group helps to categorize to some extent the familial origin of chest malignant neoplastic disease.

Prevalence of Agoraphobia In Post Neurological Illness Patients During Covid-19

Rajameena R; Vignesh Srinivasan; Prathap Suganthirababu; Kumaresan A; Divyalaxmi P; Lavanya Prathap

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 533-539

Objective: Agoraphobia is generally been defined as a fear of appearing in public places, particularly the places which are too empty or too crowded. In many situations this anxiety leads these people to avoid certain situation or requires a accompany when he travelling outside the home or staying alone in home. Agoraphobia can be observed in any gender of any age group. Methods: Patients with neurological illness who came to the outpatient department and inpatients from Saveetha Medical College and Hospital were included in the study, according to the inclusion and exclusion criteria. All the patients were explained about the study and their informed consent was obtained. The study was approved by the Institutional Ethical committee. The participants were given the Agoraphobia Scale (AS) and their responses were documented by the therapist. The outcome measure was statistically analysed. Findings: The interpretations of Agoraphobic Scale (AS) reveals that there is an increased incidence of agoraphobia among the age group 38 to 48 years. It is also observed that female neurologically ill patients have increased incidence of agoraphobia compared to male neurologically ill patients. Incidence of agoraphobia in male neurologically ill patients is noted between 48 to 58 years. Conclusion: It is concluded that agoraphobia is prevalent in neurologically ill patients during covid-19 pandemic affecting their psycho-social behaviour and their ability.

Effectiveness Of Kinect Based Games On Balance And Gait In Geriatrics: A Single Case Study

Keerthana A k; Kumaresan A; Prathap Suganthirababu; Vignesh Srinivasan; Priyadharshini Kumar; Aravind Ganesh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 356-364

Background:
Every year, about 20% of the elderly in the United States suffer from balance issues. 68 percent of these patients have an unbalanced state and fear of fall. Balance problems are particularly frequent among the elderly, and they increase the chance of falling and constitute a serious health risk. Balance problems can significantly restrict everyday activities and are linked to depression and a lower quality of life.
Aim: The aim of this research isdetermining the effectiveness of kinect based games on balance and gaitin geriatrics.

Effect of Low- Level Laser Therapy in the management of Carpal Tunnel Syndrome - A Systematic Review

Jannani T.P; Prathap Suganthirababu; Kumaresan A; Vignesh Srinivasan; Divyalaxmi P; Aravind Ganesh; Swetha Hari

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 333-339

Carpal tunnel syndrome is by far most noticeable kind of peripheral compression neuropathy (CTS). The great majority of cases are idiopathic, with median nerve compression caused by nonspecific tenosynovitis. The goal of this research is to test the efficacy of low-level laser therapy (LLLT) in the intervention of CTS. The study intended to undertake a thorough review. Studies were gathered using databases including PubMed Central, Google Scholar, Rehab Data, Research Gate, and SAGE Journals. Reviews and case study were not included, but clinical research and randomized controlled trials were. Using keywords, 134 manuscripts were screened, 118 were discarded, 16 were included, and three were eventually retrieved for analysis. The study looked at the feasibility of LLLT in treating CT syndrome. Pain incidence alleviation and increased functional performance in persons with the syndrome of carpel tunnel was investigated in this study.

EFFECTS OF DANCE-BASED MOVEMENT THERAPY ON BALANCE AND PREVENTING FALL IN CEREBELLAR ATAXIA: A CASE STUDY

Thanthoni S; Kumaresan A; Jagatheesan Alagesan; Aravind Ganesh; Rajkumar Krishnan Vasanthi

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 402-409

Background: Individuals with cerebellar ataxia in its later stages frequently have major balance and immobility issues. There are currently no effective rehabilitation programmes for people with cerebellar ataxia that can assist them improve their motor impairment.
Objective of the study:

To determine the efficacy of dance-based movement therapy on balance in subjects with cerebellar ataxia, as well as to determine the effects of dance-based movement therapy on preventing falls in cerebellar ataxia subjects.
To determine the effects of dance-based movement therapy on balance in subjects with cerebellar ataxia, as well as to determine the effects of dance-based movement therapy on preventing falls in cerebellar ataxia subjects.

Fluctuating asymmetry of dermatoglyphics and the lifetime estrogen exposure in breast cancer risk – an epigenetic perspective

Lavanya Prathap; Prathap Suganthirababu; Kumaresan A; Vignesh Srinivasan; Jagatheesan Alagesan; Deepthi Ganesan

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 491-499

Background: Through an epigenetic mechanism, a woman's total lifetime oestrogen exposure accumulates changes in her DNA methylation pattern. These changes can influence the developing fetus and the resulting epigenetic aberrations is said to be reflected in the dermatoglyphic patterns.  Fluctuating asymmetry (FA) is the difference of dermatoglyphic patterns between the right and left hand. Aim: To explore the association of FA of dermatoglyphics with the reproductive factors in an epigenetic perspective to identify breast cancer risk. Methods: The participants are grouped into three based on the selection criteria as a breast cancer, high risk and control group. The data are collected through digital photographic images. The variables include FA of the finger ridge count (FRC) of Thumb, Ring Finger, and the A-B Ridge Count. The variables of reproductive factors includes increased menstrual age, Nulliparity and first full-term pregnancy >30yrs, and Positive Family History.  Result: Among the reproductive factors involved in the study, The FA thumb is strongly associated with increased menstrual age, FA ring finger is strongly associated with nulliparity and FA subtotal ridge count is observed to be strongly associated with increased menstrual age at significance level of p<0.0001. Age at first full term pregnancy is not significantly associated with any of the dermatoglyphic variables Positive family history is significantly associated with all the dermatoglyphic variable with p<0.0001.Conclusion: FA of dermatoglyphics aids to identify the in-utero epigenetic aberrations of a females linked to breast cancer risk.

Comparative study of stretching versus strengthening exercise for anterior shin splint

Pavithra M; Ramana K; Prathap Suganthirababu; Kumaresan A; Vignesh Srinivasan; Aravind Ganesh; Rajesh G

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 443-449

Aim:This study aims to demonstrate that stretching exercises in the anterior jaw splint are more effective than strengthening exercise.
Objective:The goal of this research is to see how stretching and strengthening exercises affect athletes.
Methodology:20 subjects based on addition and exclusion criteria, study system: Individual of SCPT. Materials: mat, towel, steps. Sample technique: Random control technique. Study Design: Pilot Study. Sample mode: Convenient model: Outcome measures: NPRS, MTSS (intermediate tibial pressure syndrome level). The intervention was given for 4 weeks, 5 days / week. The NPRS and MTSS baseline analysis was performed before the intervention began. Lessons were given at 4 weeks of intervention, followed by a follow-up test to investigate the long-term effects of the intervention. Because the difference between post-test I and post-test II was considerable, the results were delayed.when the SD values were compared.
Conclusion:Therefore, it has been concluded that stretching exercises are more effective than strengthening exercise in reducing the NPRS and MTSS of athletes. 

The Impact Of Clinical Pilate Exercise On Balance And Functional Mobility In Idiopathic Parkinson Disease Patients: A Case Study

Pavithra S; Kumaresan A; Jagatheesan Alagesan; Aravind Ganesh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 379-385

Physiotherapy has been recommended for a 68-year-old retired farmer (female) who has been diagnosed as initial idiopathic Parkinson's disease. A summary of the major outcomes is included in the case study, as well as documentation of her intake assessment through a 5-week follow