Online ISSN: 2515-8260

Author : Agarkhedkar, Sharad

Clinicopathological Profile Of Significant Cervical Lymphadenopathy In Childern

Pramod Jog; Apurva Jonnalagadda; Sharad Agarkhedkar; Y Naga Akhil; Sindhuja Reddy

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 1547-1559

Aim:  clinicopathological profile of significant cervical lymphadenopathy in children
Material and methods: This study was retrospective and descriptive. Data has been taken from the case files of all patients seen at the Dr. D. Y. Patil Medical College and Hospital, Pune(2021-2022). The age ranged from 1 month to 12 years.The Health Research and Ethics Committee of the Dr. D. Y. Patil Medical College and Hospital, Pune approved the study and waived the requirement for informed consent.
Results: 50 patients, 72% IP and 28% OP, presenting the symptoms associated with lymphadenopathy were included in this study out of which 62% were male and 38% were female. The median age of presentation was observed to be 6.9 years. Swelling in neck as one of the symptoms was present in majority of patients (90%). Fever (70%), cough (70%), loss of appetite (40%), and sore throat (36%) were the other major symptoms shown by the patients. More than one symptom was shown be 68% of the patients. Majority of cases had lymph node of size 1-2 cm (76%), firm consistency (84%) and mobile (66%). The mot common site of inflammation was anterior cervical (48%) followed by posterior cervical (34%). Tenderness of lymph node was absent in 79% of the cases. Associated findings included tonsillitis (24%), ear infection (16%), hepato/spleenomegaly (16), orodental infection (6%), skin lesion and rash (4% each). Blood counts evaluation showed neutrophilia in majority of cases (56%), followed by leucocytosis (52%), anaemia (32%), lymphocytosis (24%) and eosinophilia (8%). ESR was normal in 64% of the cases.  Throat culture resulted in 50% of cases showing normal commensals while as streptococcus and staphylococcus was found in 33% and 16% of cases respectively. Cytological examination revealed reactive lymphadenitis in 46% cases, tubercular lymphadenitis in 32% cases and Suppurative lymphadenitis in 12% cases. However, 4% cases yielded inadequate aspirate. Mantoux test was negative in 66% of the cases. A total of 23 patients were sent for X-ray, out of which 12 (24%) showed normal X-ray findings.
Conclusion: The above results present the repertoire of evaluations with respect to the detection of lymphadenopathy in children. This study also emphasises the importance of considering various strategies in proper and early detection to ensure timely management of lymphadenopathy.

Prevalence of Clinical Skin Conditions seen in Pediatric Outpatient Department

Sanjana Challagalla; Revathi Yeleswaram; Shradha Salunkhe; Sharad Agarkhedkar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 1086-1093

Background: Dermatological manifestations (DM) in a developing country like India, where living conditions are poor and a variety of causes contribute to the various skin disorders, especially in children.
Aim: The aim of our study was to estimate the incidence rates of pediatric skin diseases in Pune region.
Materials and Methods: The data from departmental registries were evaluated for 260 children for 18-months period which served as a single group. The collected data comprised of all pediatric out patient department (OPD) patients aged two months to fifteen years who presented with a dermatological manifestation. The diagnosis was documented at the pediatric OPD. Mean and standard deviation were computed for quantitative factors such as age, while frequency and percentages were used to report qualitative variables such as gender and diagnoses of various skin conditions.
Results: Infections was seen in 55% of the cases, followed by allergic reactions (25.4%) and other dermatoses (19.6%). Out of 66 patients of allergic reactions, seborrhoeic dermatitis was the most common with 39.5%, followed by eczema (25.9%) and urticaria seen in 16.6. Xeroses was most common from other dermatoses which was seen in 14% of the cases. Infections such as pityriasis was seen in 52 cases, followed by tinea capitis in 20 and tinea pedis in 21 cases.
Conclusion: Patterns of skin problems serve as an indicator of community development and the quality of health care accessible. Our research provides preliminary baseline information for future epidemiologic and clinical research.

Rare Case Of Suspected Oro-Facial-Digital Syndrome In Adolescent Indian Siblings In A Tertiary Care Hospital In Western Maharashtra

Nikita Ravindra Khot; Shiji Chalipat; Sanjay Chavan; Meghna Khetan; Sharad Agarkhedkar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 1081-1085

Oro facial digital syndrome (OFDS) is a rare congenital disorder which includes a range of clinical anomalies, involving deformities of the oral cavity, face and limbs along with systemic features. The case is a 12-year old Indian girl who had  the classical features of OFDS with sensorineural hearing loss and vertebral abnormalities. Interestingly, her younger sibling also had some of the peculiar features of OFDS.This case report highlights the importance of prudent clinical and radiological findings which aid in early diagnosis of unsuspected and rare conditions as learned in this case, as it may help improve quality of life of the patient.