European Journal of Molecular & Clinical Medicine

Background: Juvenile idiopathic arthritis (JIA) is a term that encompasses all forms of
arthritis that begin before a patient is aged 16 years that persist for more than 6 weeks and
are of unknown origin. It is the most common childhood chronic rheumatic disease and
causes much disability. We investigated the relation of serum 14-3-3 η (eta) protein in
oligoarticular JIA (OJIA) and; the disease activity and severity.
Methods: This study is a case control study including 14 JIA patients and 14 control
group. Patients were (6 males and 8 females).14-3-3η was measured for all patients and
control volunteers by enzyme-linked immunosorbent assay (ELISA) technique. ANA was
measured by indirect immunofluorescence (IIF) technique. Disease activity was assessed
by the Juvenile Arthritis Disease Activity Score27 (JADAS-27). Functional ability was
assessed by childhood health assessment questionnaire (CHAQ), and disease severity was
assessed by juvenile arthritis damage index (JADI). Radiological damage was assessed by
Poznanski score.
Results: Elevated 14-3-3 η levels were detected in 5/14 (35.7%) patients. Positivity for 14-
3-3 η was significantly related to disease activity, severity and ANA. Positivity for 14-3-3 η
had no significant correlation with CHAQ or Posnanski score.
Conclusion: Serum 14-3-3 η can be detected in oligoarticular JIA patients, and appears to
correlate with disease activity, severity and (ANA). But no correlation with CHAQ or
Poznanski score.

An analysis of the literature on the theory and methodology of physical education reveals that in the theory of sports (wrestling, etc.) and in separate articles, the authors have described explosive power as a physical quality.
The manifestation of explosive force is the mechanism of its activation. As the burst time of the muscle decreases, the intensity of the bursting force increases. However, the intensity of the explosive force can also be increased by increasing the magnitude of the absolute force of the muscle.
Summarizing the above points, it can be concluded that the study of the features of the methodological basis of the formation of explosive mobility in athletes in fast-paced sports plays a certain role in solving important vital issues in sports.

The article examines the issues of ensuring the activity of students in the pedagogical process on the basis of basic concepts, the formation of the subjects' interest in the studied concepts and the motivation of students to analytical activity in the process of a reflexive approach and the development of reflection in them.

The article examines the issues of ensuring the activity of students in the pedagogical process on the basis of basic concepts, the formation of the subjects' interest in the studied concepts and the motivation of students to analytical activity in the process of a reflexive approach and the development of reflection in them

Background:
     Physical activity (PA) is defined as any bodily movement produced by the contraction of skeletal muscles that results in a substantial increase in caloric requirements over resting energy expenditure. According to the World Health Organization(WHO), physical inactivity is considered the fourth leading risk factor for global mortality. Physical inactivity is associated with excess weight and adverse health outcomes. In particular, office-based screening of activity levels and physical activity counseling coupled with regular follow-ups and community support and referrals for physical activity, have been proven effective in increasing physical activity levels. In addition, the cost of integrating physical activity counseling and referral schemes into primary health care teams has been found feasible and cost-effective Physical activity can be defined as any movement of the body that requires energy expenditure.
 
Aim of this study: To Assessment of the Prevalence of Physical Activity among Adult Patients attend primary health care centers in Makkah city, Saudi Arabia.
 
 Methodology: Cross sectional design has been adopted. The study has been conducted in Makkah city, Saudi Arabia. The present study was conducted at primary health care centres in Makkah city. Systematic random sampling was being adopted to select persons during the March to June, 2019.The sample (300).
 Results: Exercise milieu these study results showed that Positive Exercise milieu proportions (62.0%), and Negative Exercise milieu proportions (38.0% ) while  the Range  (8-22)  Mean +SD (13.254±3.215) while Time expenditure the most of them negative were(69.0%)but positive (31.0%)while the Range (6-13) Mean +SD (10.812±2.77)
 
Conclusion: Physical inactivity among Arab adults and children/adolescents is high. Studies using harmonized approaches, rigorous analytic techniques and a deeper examination of context are needed to design appropriate interventions. Physical activity likely has a greater role in promoting health in disease populations than previously thought and may confer substantial reductions in disease burden Primary health care centers in Makkah should be active and able to provide health advice and behaviour to their patients. There will a strong intention to increase physical activity among physically inactive primary care physicians (PHCPs).