Online ISSN: 2515-8260

Keywords : asphyxia

A Clinical Study of Maternalandperinatal Outcome in Pregnancy Induced Hypertension

Himabindu Sangabathula, Neelima V, Siddareddy Yashovardhini

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 4767-4777

Background:Hypertension is a prevalent and serious disorder that can cause or
exacerbate many health issues. Blood pressure is directly associated to cardiovascular
disease and mortality. Stroke, MI, angina, heart failure, renal failure, and
cardiovascular mortality are all linked to BP. As a result, hypertension is often referred
to as "the silent killer." The study's aim is to assess maternal morbidity and mortality
in pregnant women with pregnancy-induced hypertension. Birth weight, Apgar score,
NICU admission, prenatal morbidity and mortality.
Materials and Methods: During two years, pregnant women aged 21 to 40 weeks were
studied at Govt Medical College &Hospital Nalgonda (July 2019-July 2021). An 80-
patient study. The institutional ethics committee review board approved. Each patient
had a comprehensive history, clinical examination, and proforma. In all instances, the
length of hospital stay, patient recovery, perinatal outcome (birth weight, Apgar score,
NICU admission), and perinatal morbidity and mortality were examined.
Results: he present investigation found that unbooked cases had more severe
preclampsia and eclampsia. Preeclampsia patients who had not had routine prenatal
care were 40 percent unbooked. Unbooked cases have increased maternal and perinatal
mortality. In this study, 40% of NICU admissions were due to LBW/asphyxia. Overall,
50% of newborns were born underweight. PIH was a prominent cause of iatrogenic
premature birth.
Conclusion: 100% registration of pregnant women and good quality antenatal
treatment including weight, blood pressure, and urine analysis with adequate referral
mechanism to tertiary care centres.All family physicians and medical officers need to be
advised to follow a standard management protocol in a case of preeclampsia and
eclampsia with an awareness for prompt referral of women who require to be managed
by specialist. Every tertiary care centre must have specialised expertise. Though PIH is
not preventable, adequate ANC care can slow its progression and timely intervention
can significantly improve perinatal outcomes.

Histomorphological Changes In Hypertensive Placentas And Its Correlation With Foetal Outcome

Dr. Geetanjali U. Yadgire; Dr. Shobha S. Rawlani; Dr. Anupama Sawal; Dr. Deepali G. Vidhale

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 1938-1947

Placenta is an important organ which is necessary for the intrauterine growth of foetus.complications .due to Pregnancy like hypertension(PIH) affects the placenta and is the major factor to cause maternal & foetal death.
Objectives:1. To study the morphological and histological features of placenta in normal and hypertensive patients . 2.To Compare the two groups and study the correlation of their changes with the foetal outcome.
Material & Methods: 100 specimens of placentas of patients from normal as well as hypertensive group were collected from the labour room & operation theatre of Dept. of Obstetric & Gynaecology of Dr. Panjabrao Deshmukh Medical College and hospital, Amravati, Maharashtra .At first the gross features ( morphological features) of placentas were observed.. To study the histology , sections from each placenta of size 5mm were taken. This was fixed in in 10% formal saline and further histological processing of the tissue was carried out.
Observations & Results: The gross morphological features like weight, size, surface area, number of cotyledons were reduced and areas of infarction, retroplacental clot, calcification were increase in hypertensive placenta than normal placenta. (p<0.005) Similarly, the histological features like increased syncytial knots, intravillous and intervillous fibrin deposition, cytotrophoblastic proliferation, hyalinised villi, atherosis were observed in hypertensive placentas. These all changes were correlated with the foetal mortality and morbidity. And we observed that there was increase in foetal mortality and morbidity in hypertensive patients with the above histological changes in their placentas.