Online ISSN: 2515-8260

Keywords : amniotic fluid index


A COMPARATIVE STUDY OF THE EFFECT OF ORAL AMINO ACID SUPPLEMENTATION VS INTRAVENOUS AMINO ACID INFUSION ON AMNIOTIC FLUID INDEX AND PERINATAL OUTCOME IN PREGNANCIES COMPLICATED BY OLIGOHYDRAMNIOS AND FOETAL GROWTH RESTRICTION

Dr. AKRUTI SHINDE; Dr. MEHUL SALVE

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 2018-2026

BACKGROUND: The primary function of amniotic fluid is protection of the growing foetus while providing nutrition. A considerable amount of research has been conducted to evaluate interventions to improve amniotic fluid index and the subsequent impact on foetal growth restriction and oligohydramnios. However, there isn't any conclusive evidence hence this study aims to compare the effect of oral amino acid supplements and intravenous infusions in pregnancies with oligohydramnios and foetal growth restriction. 
AIM: To compare the effect of oral amino acid supplementation vs intravenous amino acid infusion on amniotic fluid index and perinatal outcome in pregnancy complicated by oligohydramnios and foetal growth restriction
OBJECTIVES: To compare the effectiveness of oral amino acid supplementation vs intravenous amino acid infusion in pregnancy having oligohydramnios and foetal growth restriction. To study the increase in amniotic fluid index in pregnancy with foetal weight gain. To study the interval growth rate of baby after two weeks and four weeks of therapy.
MATERIAL AND METHOD: This Semi experimental study will be conducted in Department of Obstetrics and Gynaecology, AVBRH, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha. A total of 104 clinically and sonographically proven cases of foetal growth restriction & Oligohydramnios in third trimester attending antenatal clinic or admitted in wards, fulfilling the exclusion and inclusion criteria will be comprise the study groups. After providing oral supplements or intravenous infusions arbitrarily, repeat ultrasonography will be done after two weeks and four weeks of therapy.
EXPECTED RESULTS: We compare from our results the effect of oral amino acid supplementation vs intravenous amino acid infusion on amniotic fluid index and perinatal outcome in pregnancies complicated by oligohydramnios and foetal growth restriction.

A Potential Association of Neonatal Outcome in Comparison Between Amniotic Fluid Index and Deepest Vertical Pocket in Supine and Left Lateral Position

Azza Gamal Abd Allateef, Anwar Ezzat Esmail, Amal Mohamed Al Anwar, Mostafa Abdo Ahmad

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 5943-5950

BACKGROUND:The amniotic fluid plays an important role in fetal growth. Measurement
of amniotic fluid volume can be made directly, indirectly, or estimated sonographically.
Thetwo standardmethods of sonographic evaluation of amniotic fluid volume are single
deepest pocket (SDP), and amniotic fluid index (AFI). We aimed to compare different
methods of measuring AFI for increasing its accuracy and, subsequently neonatal
outcome.
METHODS: A cross-sectional study was conducted at the Obstetric and gynecological
departmentfrom May 2019 to February 2020. The study included 80 pregnant women (18-
35) years old whose gestational age before 24 weeks of gestation and not hypertensive or
diabetic. Women were assigned to AFI or SVDP measurement for estimation of amniotic
fluid volume in lateral decubitus Position at 36 weeks, thenfollow-up measurements of AFI
and SVDP were performed at 38 – 40 weeks of gestation at both postures.
RESULTS: At 36 weeks of gestation, there was a statistically significant increase in AFI
and VDP values on maternal change position from supine to lateral decubitus.Also, a
similar significant increase in AFI and VDP values on changing maternal position at 38-
40 weeks of gestation.There was a significant increase in AFI values with the progress of
gestation age at the supine position. Without significant difference at lateral decubitus
position, but there was a significant increase in VDP values with the progress of gestation
age at both positions.There was a significant negative correlation between AFImeasured
on lateral decubitus position at 36 weeks and incidence of AF-stained meconium and need
for NICU admission alsothe incidence of respiratory distress as well as there was a
significant negative correlation between all VDP values and need for NICU admission and
the incidence of respiratory distress.
CONCLUSION:We concluded that the VDP method is the favorable method to estimate
amniotic fluid volume.