European Journal of Molecular & Clinical Medicine

Background: In the course of any living thing's existence, ageing is a normal and expected component of the process of development. There is very nothing that can be done to slow down the ageing process, as it is a natural part of life. It is not merely a biological phenomenon, but also has psychological and social ramifications for humans.

Aim: To evaluate the psychiatric morbidity using MINI questionnaire in patients diagnosed with
CKD.
Materials and Methods: Total 170 patients were interviewed over a period of one and a half
year starting from January 2014. Each patient was assessed twice: at the baseline and after 3
months. Patients were approached and after obtaining their consent, information was collected
about their socio-demographic details like age, sex, marital status and religion, duration of renal
illness (CKD). Each patient was then screened for psychiatric morbidity using MINI
questionnaire. Patients were then divided into two groups: those having psychiatric morbidity
and those without. The collected data was compiled in MS Excel sheet 2007. For analyses of this
data SPSS version 20 for Windows 7 was used.
Results: The study population consisted of patients between the ages of 18 to 72 years with the
mean age of 40.8(SD=14.8). There were 120 males (70.6%) and 50 females (29.4%) in the study
population. There were 134 married (78.8%), 30 single (17.6%) and 6 widowers (3.5%) in our
study population. 42 (24.70%) had a diagnosable psychiatric morbidity on Mini International
Neuropsychiatric Interview. The most common psychiatric diagnosis found in our study was
Major depressive disorder that was seen in 88.09% (n=37) patients followed by Generalized
anxiety disorder, which was seen in 3 patients (7.14%). Psychiatric morbidity was highest in the
age group of 51-60 years. Significant association was found between age group and psychiatric
morbidity (p<0.001). The impact of duration of illness and psychiatric morbidity revealed
significant association between these two factors (p<0.0001).

Background/Rationale: Skin is the most visible organ that defines our appearance and plays a significant social communication role to a great extent. Human beings are often concerned with their external physical appearance, which is directly related to the health of the skin, and if any disease triggers a change in the skin's natural appearance, it causes distress to the individual. Chronic diseases such as Vitiligo, Psoriasis, and Pemphigus severely dagrades the quality of life ( QOL) of affected individuals. ,Psychiatric morbidity was shown by Indian patients as stress ,anxiety depression, lower self-esteem, adjustment disorders, and sleep disturbance, and are vulnerable to various psychiatric disorders such as severe depression and suicidal ideations. The involvement of a chronic illness is typically associated with lower health-related quality of life ( HRQOL), and severity of the disorder often affects HRQOL. Objectives: To evaluate the quality of life of patients having Psoriasis, Vitiligo and Pemphigus Vulgaris and To explore the correlation between disease severity and quality of life. Methods: Prospective Cross sectional Study will be carried out in 65 patients with chronic skin diseases, attending Out Patient Department of Dermatology, AVBRH, JNMC, Sawangi, Wardha, will be Registered after having considered different conditions for inclusion and exclusion. A detailed history will be taken, severity index will be calculated and questionnaire, DLQI, HRQOL will be given to the patients. Results: The result would be undertaken in SPSS software. Conclusion: The conclusion will be based on findings for study protocol.