Online ISSN: 2515-8260

Keywords : Elderly Patients


Thyroid Dysfunction Prevalence in Elderly Patients with Chronic Liver Disease in Zagazig University

Mohamed Mohamed Hassaan, Zeinab Maher Mohamed, Aya Hefny Ibrahem, Mayada Mohamed Mousa

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 493-502

Background: Cirrhotic patients are more liable to thyroid dysfunction especially
hypothyroidism and may have thyroiditis and hyperthyroidism. The aim of this
work is the evaluation of thyroid dysfunction in elderly patients with chronic liver
disease. Patients and methods: A cross-sectional study included 54 elderly patients
with clinical, biochemical, and ultrasound evidence of cirrhosis of liver which was
carried out in Internal Medicine Department, Faculty of Medicine, Zagazig
University Hospitals. All subjects included in this study were elderly over 65 years
and subjected to through clinical examination and full history taking with special
stress on age, sex, comorbidities, medications, symptoms of hepatic decompensation
and symptoms of hypothyroidism or hyperthyroidism. The technical part was done
at Biochemistry Department in Zagazig University. We assessed complete blood
count, serm bilirubin, serum albumin, serum ALT and AST, serum creatinine,
serum urea, PT, PTT, INR, TSH, free T3, T4 and lipid profile. Results: There was a
statistically significant positive correlation between serum TSH and weight, BMI,
Child score, total, direct bilirubin, INR, serum cholesterol, LDL cholesterol and
triglycerides. There is significant negative correlation between TSH and total
leucocytic count, platelet count, serum albumin. There was a significant negative
correlation between free T4 and both weight and BMI. There is significant positive
correlation between free T3 and total leucocytic count, and platelet count. There is
non-significant correlation between free T3 and neither weight, BMI, age,
hemoglobin, serum albumin, serum creatinine, ALT, AST, INR, LDL or HDL
cholesterol There was a significant negative correlation between child score and
TSH while there is significant positive correlation between child score and both Ft4
and FT3. There is significant relation between presence and degree of ascites and
all of free T4, free T3 and TSH. Conclusion: There is important relation between
Child pough class and all of free T4, free T3 and TSH. There is significant relation
between grade of hepatic encephalopathhy and all of free T4, free T3 and TSH.

Clinical characteristics comparision of the types of paroxysmal supraventricular tachycardia attack between young and elderly patients

Si Dung Chu; Song Giang Tran; Minh Thi Tran; Khanh Quoc Pham

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 3954-3965

This study is carried out to describe types of clinical characteristic of paroxysmal supraventricular tachycardia attack (PSVT) between young and elderly patients who underwent cardiac electrophysiology test. This is a cross sectional descriptiveand prospective study. 182 patients who were diagnosed with PSVT attack underwent cardiac electrophysiological test at Vietnam Heart Institute during 01/2014-05/2017. The patients were divided into two groups: Group I (n=93) is the young patients (< 60 years of age) and Group II (n=89) is a elderly patients (≥ 60 years of age).: Group I (young patients) accounted for 51.1% and Group II (elderly patients) made up 48.9%. vThe rate of PVST attack in female was 70.0% while that in male was 29.1% (P>0.05); the mean age of elderly patients was higher than younger patients (p < 0.0001). The PVST attacks have moredate positive correlation with structure (R = 0.355) and hypertension (R = 0.314), there are differences between both groups in the structure and hypertension. The structure and hypertension rates of patients in elderly petients group were higher than those in young patients group (p < 0.0001), there is a strongly postive correlation between the structure and hypertension patients (R = 0.966, p < 0.0001). Characteristics of PVST attack are 68.3% of atrioventricular nodal reentrant (AVNRT) and 29.6% of atrioventricular reciprocating tachycardia (AVRT) attacks; The AVNRT and AVRT attack rates in female were 74.8% and 61.8% respectively, whereas the AVNRT and AVRT attack rates in male were 25.2% and 28.2% respectively (p > 0.05). PVST attacks were more common in female patients than in male patients. the likelihood of having AVNRT was higher compared to AVRT attacks, and the mean age of AVNRT and AVRT attack in the elderly patients was higher than that in young patients.