Online ISSN: 2515-8260

Keywords : thrombosis

Magnetic resonance venography evaluation in cerebral venous thrombosis – A retrospective stu

Dr Nipa Hathila, Dr Harish Chandra Chaturvedi, Dr. Shekhar Karnawat, Dr. Shrinidhi Kulkarni, Dr. Kanaram Yadav

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1418-1424

Introduction: Cerebral venous thrombosis is a relatively uncommon disorder which has
an estimated annual incidence between two to seven cases per million in the general
population. 1 The incidence was likely underestimated before the advent of prompt noninvasive
imaging methods. It is estimated that five to eight cases per year might be seen
at a referral centre. Cerebral venous thrombosis or occlusion by extrinsic compression
that eventually progresses to a complete occlusion is an elusive diagnosis because of its
non-specific presentation and its numerous predisposing causes which can precipitate
the condition. It often affects young and middle-aged patients which more commonly
involved in women. It is an uncommon cause of cerebral infarction relative to arterial
disease which is an important consideration because of its potential morbidity. The
imaging characteristics of CVT that can be observed through MRI include: (1) brain
parenchymal imaging that appears in the form of non-specific lesions, such as
intracerebral hemorrhages or infarcts, edema, isolated or associated with infarcts or
hemorrhages, and it can even be considered normal in about 30% of patients.9 MRV
features include non-visualization of the arterial & venous vessels (i.e., no flow), flow
defect and presence of collaterals at the site of occlusion.

Features Of Thrombophilia In Covid-19

Dadajanov Utkur Dadajanovich; Mamatkulova Feruza Xaydarovna; Ruziboeva Oyjamol Narzullaevna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 5199-5205

from this article we see that why COVID-19 causes thrombosis, A thrombus is a mixture of platelets, erythrocytes and fibrin protein, which begin to accumulate on the wall of the damaged vessel. gradually it thickens and hardens, but in general it resembles a viscous substance, similar to jelly,it can be unambiguously stated that with this virus, from the very beginning, there is an activation of hemostasis, intravascular blood coagulation and thrombus formation in small-caliber vessels of vital organs. In this case, not only the lungs are damaged, but the blockade of microcirculation and its irreversible nature determine the outcome of the disease.

An Unusual Presentation of Systemic Lupus Erythematosus as Evan Syndrome: A Case Report and Review Literature

Ali Al Bshabshe; Hamdan Al-Shehri; Ali Assiri; Abdulmoneim Jamil

European Journal of Molecular & Clinical Medicine, 2018, Volume 5, Issue 1, Pages 37-40

Evans syndrome is a rare autoimmune disorder with an unknown etiology. In this paper, we report the case of a 32-year-old Saudi woman living with Evans syndrome for more than 8 years (post-splenectomy) who was also diagnosed with systemic lupus erythematosus (SLE). She was admitted to our Hospital with severe headache and confusion due to cerebral venous thrombosis. The major hematologic manifestations of SLE were pancytopenia and the antiphospholipid syndrome, which are indicators of disease activity when all other possible causes are excluded. The patient was treated with anticoagulation and immunosuppressive therapy and subsequently showed significant improvements in thrombosis, thrombocytopenia, and anemia. This case report provides an overview of the association between Evan syndrome and SLE.