Online ISSN: 2515-8260

Keywords : Leprosy


Determination of random blood sugar, alkaline phosphatase and zinc levels in individuals with leprosy

Ansuman Dash, Lingidi Jhansi Lakshmi, Anju Choudhary, Doddigarla Zephy, Qurie Madhura

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 2048-2056

Objective: The current study aimed to compare the levels of zinc, alkaline phosphatase, and random blood sugar in people with leprosy to those in healthy controls from the Bundelkhand area. The second objective was to compare the correlation between study parameters in the leprosy group and the healthy control group. Material & methods:  The research was carried out in the Department of Biochemistry at Maharani Laxmi Bai Medical College (MLBMC) in Jhansi. In the healthy control group, forty human beings with normal glycemic status were age and gender matched. The leprosy patient group contained forty leprosy patients who were receiving treatment. Leprosy disease was diagnosed in accordance with the world health organization guidelines. Results: Age difference between the two groups was not statistically significant in the present investigation. Whereas, we found a statistically significant contrast between the two sets of data we analyzed, including RBS, ALP, and serum zinc levels. Leprosy patients showed a positive link between ALP and zinc, and a negative correlation between age and RBS; RBS and serum zinc. A positive connection between ALP and zinc was seen in the control group. We conclude that periodic monitoring of zinc concentrations in leprosy people may be prudent since zinc deficiency worsens insulin resistance and may lead to greater loss through urine.

A MORHOLOGICAL ANALYSIS OF SKIN BIOPSIES IN HANSENS DISEASE

Dr.C.Aparna, Dr. G.Harinath, Dr. K.Sharada Devi, Dr. A.Shanmugapriya, Dr. K.Harika Reddy, Dr. R.Sugatamil

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 3172-3179

 Background; Leprosy still continues to be an important public health problem. The present study was undertaken to study the histopathological features of  leprosy in skin biopsies and to categorize them into various types based on microscopy, bacterial index to correlate with clinical presentations whenever possible.  Aim;To know the prevalence of Leprosy in our Institute with Clinico-Histopathological correlation.  Objectives;To know the distribution of various types of Leprosy in our Institute.To know the sensitivity and overall correlation of Histopathology and Bacterial index in diagnosing various types of Leprosy Material and methods :We have done the study on a Sample size of 55cases.  Results:  Borderline Tuberculoid leprosy constituted  the  maximum percentage of cases. Conclusion : Correlation between clinical, bacteriological and histopathology was 100% in diagnosing BB,IL, and ENL followed by BT.

An Understanding of A Clinico Pathological Correlation In Leprosy In A Tertiary Care Teaching Institution.

Nishant Saxena, Nimisha Saxena, Shilpa Mittal , Harsh Sharma

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 409-420

Background: Leprosy caused by mycobacterium leprae is a chronic granulomatous disease that mainly
affects peripheral nerves and skin. Depending upon the immune status of the individual it manifests var ious
clinical and pathological forms. Histopathology plays an important role in the diagnosis of clinically suspicious
cases and helps in exact classification of various subtypes and types which therefore helps in deciding the
treatment plan and cure. Vari ous inflammatory disorders also mimics clinically to leprosy therefore exact
diagnosis plays an important role for early treatment. So this study is undertaken to correlate the clinical
diagnosis with histopathological findings which plays crucial role in patient management.

EXPERIMENTS ON SANITARY HYGIENE OF ANCIENT KARAKALPAKS AND METHODS OF PREVENTION OF INFECTIOUS DISEASES

A.J. Kurbanbaeva; U.A. Aleuov

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 1342-1347

In all periods of human development, every nation around the world had its own
special and personal folk descriptions and methods of treatment. Folk healing originated in the
first stages of the formation of human life. She was not guided by any scientific rules. only with
the help of approximate indicators of the development of achieving the properties of a kind of
folk treatment, there was a further continuation. However, it is not so difficult to determine the
origins of the history of healing, the objects and goals of treatment are always similar, relevant
and common. Only the concepts of diseases, the ways of their presentation and the practice of
treatment were not always similar to each other. this does not mean that the number of diseases
has increased, just that identical methods of treatment have been formed.