Online ISSN: 2515-8260

Keywords : Candida

Surveillance of microorganisms and their drug sensitivity patterns in diabetic UTI patient at a tertiary care teaching hospital

Santosh Singh, Rajashree Panigrahi, Ishwara Chandra Behera, Dr. Debasmita Dubey

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1952-1966

Background: Urinary Tract Infection (UTI) is one of the common infections affecting people, both from the community and hospital. The causative pathogens for UTI and their drug sensitivity patterns vary from region to region. Changes in their genetic constituents with time might be the reason.
Aim: In this study, we aimed investigate the profile of common uropathogens and assess their antibiotic sensitivity patterns with commonly used drugs for UTI patients.
Materials and methods: In this study, 153 urine samples were analyzed with routine microscopy, culture and sensitivity for a period of six months at Institute of Medical Science and SUM Hospital, Bhubaneswar, Odisha. Both bacteria and fungi were used for drug sensitivity test.
Result: A total no. of 54Gram positive bacteria and 40 Gram Negative bacteria were isolated. S. aureus was the most common GPC isolated and P. aeruginosa was the most common GNB. E. coli was the second most GNB which showed resistance to Cephalosporins and Aminocoumarin group. 4 Candida species were isolated, to which Clotrimazole was the most susceptible antifungal agent. Staphylococcus sp. showed resistance to β-lactams and Macrolides group of antibiotics. Shigella sp. showed resistance to β-lactams. C. albicans was found to be the common Fungi isolated, followed by C. krusei.
Conclusion: Since the drug sensitivity pattern changes from place to place and varies from time to time. The culture sensitivity therapy should be practiced before empirical administration of antibiotics.

Synthesis and Characterization of Zinc Oxide Nanoparticles (ZnO NPs) and their Biological Activity

Sumit Yadav Dr. Sourabh Jain Dr. Veenu Sisodia

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 9524-9541

Zinc Oxide Nano particles promise an important role in various industries like pharma, fertilizer, textiles and garments due to their specific properties such as anti-fungal, antibacterial and anti-rust. Zinc oxide nanoparticles were prepared by eco-friendly wet chemical method. Formation of ZnO nanoparticles was confirmed by using spectroscopic and microscopic investigations. Samples were characterized using Ultra-Violet Spectroscopy, Fourier Transform Infrared, Scanning Electron Microscopy, Transmission Electron microscope, X-ray Diffraction and four probe Voltage-Current characterizations. Antifungal and antimicrobial activity  

Candida Species – Morphology, Medical Aspects And Pathogenic Spectrum

Shubham Koundal; Louis Cojandaraj

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 4015-4021

Emergence of candidal infections are increasing from decades and found to be a leading cause of human disease and mortality. Candida spp. is one of the communal of human body and is known to cause opportunistic superficial and invasive infections. Many of mycoses-related deaths were due to Candida spp. Major shift of Candida infection towards NAC (non-albicans Candida) is matter of concern worldwide. In this study we had given a systemic review about medically important Candidaspp. Along with their morphological features, treatment and drugs. Spectrum of the pathogen is also discussed. Morphology of Different Medically Important Candida Species with their medical aspects along and pathogenic spectrum. Corn meal agar morphology along with anti-candida drugs has been discussed. The study is done after considering various published review’s and the mycological studies.