Online ISSN: 2515-8260

Keywords : Serum

Significance of Serum Samples for Protein Studies

Pushpalakshmi Gangadharan; Ananthi Sivagnanam; Balasankar Thangasamy; Ambika Pushparaj; Premkumar Karunakaran; Raja JeyaSekar R; Megala Jayaraman; Pushparaj Arunachalam

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 740-749

Serum proteins also known as blood or plasma proteins are proteins present in
blood that serve many different functions, including transport of lipids, hormones,
vitamins, and minerals in the circulatory system and the regulation of acellular activity
and functioning of the immune system. Other blood proteins act as enzymes, complement
components, protease inhibitors, or kinin precursors. Although serum proteins have very
high concentrations, they exhibit an uneven distribution in terms of composition. That is,
only about 22 proteins account for 99% of all the serum proteins. These include serum
albumin, globulins, and fibrinogen. The remainder 1% of blood proteins is composed of
low abundance circulatory proteins, as well as proteins secreted by live, apoptotic, and
necrotic cells. Most blood proteins are secreted by the liver and intestines except for the
gamma globulins, which are synthesized by the immune system. In this study we aimed to
analyse the serum samples taken from gastric cancer patients and compared with healthy
serum samples. We estimated the serum samples using Bradford method of protein
estimation and performed SDS PAGE analysis. This article highlights the importance of
serum sample collection, handling and storage with respect to consideration towards
protein-based studies using serum samples.

Serum Uric Acid Level and Severity of Ischemic Stroke

Aparna P. Patange; Kapale R.J.

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 86-89

A stroke is the third most common cause of death and the fourth most common cause of infection. Stroke is characterized by the WHO as a clinical condition involving the rapid development of clinical indications of a central aggravation of cerebral capacity lasting more than 24 hours or causing death without a clear reason other than a vascular source. In the present study, a large part of the cases of intense ischemic stroke were found among the males. In the present study, mean cholesterol values, triglyceride values are directly proportional to the severity of the ischemic stroke, among the study subjects. In the present study, 8% cases died, while 92% discharged at home. The current study proved the association of serum uric acid levels with the severity of the acute ischemic stroke.

Characteristics Of Exchange Of Essential Microelements Of Copper And Zinc In Healthy Fertilized Women And Women With Combined Copper And Zinc Deficiency State

Sohibova Ziyoda Rakhmonovna; Akhmedova Nilufar Sharipovna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 3332-3335

The study of various aspects of the problem of common hypomicroelementosis caused by a deficiency of essential trace elements copper and zinc, in particular among women of fertile age, in the population is extremely relevant and important, taking into account the social significance and importance of this population for society , because of what the condition will be health in a given population depends on the state of such important socially significant processes as the healthy development of future generations