Online ISSN: 2515-8260

Keywords : Hypomagnesemia


Hypomagnesemia Associated with Chronic Renal Diseases: A Review Article

Amr El Santawy, Ayman Riyadh, Maher Boraei, Mohamed Fouad

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 4276-4287

Magnesium (Mg2+) is an essential cation for multiple processes in the body. The kidney plays a
major role in regulating the Mg2+ balance. In a healthy individual, total-body Mg2+ content is
kept constant by interactions among intestine, bones and the kidneys. Hypomagnesaemia is
involved in the pathophysiology of hypertension, vascular calcification and metabolic
derangements including diabetes mellitus and dyslipidemia, which are all risk factors for
cardiovascular disease; the leading cause of mortality and morbidity in all stages of chronic
kidney disease (CKD)including end-stage renal disease (ESRD).Magnesium is the second-most
abundant intracellularcation after potassium and, overall, the fourth-most abundant cation
after sodium, potassium, and calcium, and plays important roles in a number of biological
processes in the human body such as protein synthesis, muscle and nerve transmission,
neuromuscular conduction, and signal transduction.In case of chronic renal diseases, renal
regulatory mechanisms may be insufficient to balance intestinal Mg2+ absorption. Usually Mg2+
remains normal; however, when glomerular filtration rate declines, changes in serum Mg2+ are
observed.

INCIDENCE OF HYPOMAGNESEMIA AND HYPOCALCEMIA ON DAY ONE AND DAY FOUR IN NEONATES BORN

G. G. Joag; S. Y. Ingale; D. B. POTDAR; S.B Karanjkar; Kanvikar Reshmi

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4125-4129

Present study is to assess the incidence of hypomagnesemia and hypocalcemia on day one and day four in neonates who are born in a tertiary care hospital of western maharashtra. Study done at KRISHNA Hospital, Karad. Children s who were born congenitally, and who met the eligibility criteria, were studied in the obstetric department of Krishna Hospital. 2.5 ml of cord blood was collected on day 1 of life in a plain bulb. On Day 1 of life, Hypocalcemia occurred in 0.5% of the 400 neonates studied. On Day 1 of life, Hypomagnesemia occurred in 1% of the 400 neonates studied. On Day 4 of life, Hypocalcemia occurred in 10.5% of the 400 neonates studied. On Day 4 of life, Hypomagnesemia occurred in 0% of the 400 neonates studied. No cases of Hypocalcemia with Hypomagnesemia occurred together at the same time either on Day 1 of life or on Day 4 of life.