Online ISSN: 2515-8260

Keywords : Fine needle aspiration cytology


A RETROSPECTIVE RESEARCH TO EVALUATE THE ROLE OF FINE NEEDLE ASPIRATION CYTOLOGY IN THE DIAGNOSIS OF THYROID LESIONS

Yadav P; Kolta N; Kaundal V

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 1115-1120

Aim: To evaluate the role of Fine Needle Aspiration Cytology in Diagnosis of Thyroid lesion. Materials and Methods: A retrospective research was conducted at the Department of Pathology, Assiut University and Hospital, Egypt. An overall total of 200 patients with a single thyroid nodule who met the inclusion criteria were included in the research. In the case of fine needle aspiration cytology, the sensitivity, specificity, positive predictive value, and negative predictive value were determined based on histopathologic examination, which was the gold standard. Results: There were 120 females and 80 men in attendance, resulting in a female to male ratio of 1.5:1. The patients' ages varied from 14 to 71 years, with a mean age of 43.69 years plus standard deviation (12.49 years). The majority of the patients are between the ages of 30 and 40. Neck oedema was the most common symptom among these patients (100 percent), followed by vocal cord palsy (15 percent), breathing difficulties 11 percent, and dysphagia 9 (4.5 percent), respectively. The thyroid nodule varied in size from 2 to 6.9 cm, with a mean of 4.51 +/- S.D. 1.89 cm and a standard deviation of 1.89 cm. Based on the results of this study, nodular goitre accounted for 52 percent of solitary thyroid nodules, with benign cyst accounting for 32 percent of benign lesions, 33 percent of follicular carcinoma, 17 percent of papillary carcinoma, and three cases being suspicious of neoplasm among the benign lesions. Conclusion: FNAC has key rule in diagnosis of solitary thyroid nodule because it is safe, minimally invasive and cost effective diagnostic tool. 

SENSITIVITY AND SPECIFICITY OF FINE NEEDLE ASPIRATION CYTOLOGY [FNAC] IN A THYROID SWELLING

H.V. Nerlekar; A. M. Shah; C.Z. Perdeshi; Amol D. Langale; Umesh B. Choughele

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4156-4161

The current study was observational study undertaken to study sensitivity and specificity of FNAC in a thyroid swelling. It was observed that majority of patients with goiter were in age group 31-40 years. The majority of patients with goiter were females 50 (89.29%) as compared to males 14 (73.68%). The carcinomas were also more prevalent in females as compared to males. The results of thyroid cytology must be assessed in conjunction with the clinical findings and other investigations like TFT and USG findings, in view of the possibility of false negative or false positive cytological diagnosis. The viability and applicability of cell pattern analysis in applying pattern analysis to the understanding of thyroid cytology is also seen in this study.