Online ISSN: 2515-8260

Keywords : Ketorolac

Comparison of intravenous ketorolac and tramadol as Adjuvants in control of post-operative pain in patientsundergoing laparoscopic surgeries under general Anesthesia in a tertiary care hospital

Vinuth K Murthy, Vridhi Rajan, Abraham AA

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 2862-2870

Aim and Objectives:To assess and compare the analgesic effects of adjuvants like
intravenous Ketorolac and Tramadol in laparoscopic surgeries on post-operative pain and
their side effects.
Methodology: In this quasi experimental study,after approval from ethical committee and
written informed consent taken from 90 patients of ASA physical status I,II of either sex
scheduled to undergo elective laparoscopic surgeries under general anaesthesia were
enrolled.Patients were randomly divided into one of the two groups of 45 patients each,
patient received either Ketorolac (Group K) or Tramadol (Group T) 30 minutes before
extubation. The degree of post-operative pain was assessed using VAS at 0, 2, 4 hours post
operatively upto 24 hours and the need of rescue analgesic and the side effects of both drugs.
Results: The pain score at 0 hours were more than 4 in both the groups.
Statisticalanalysisshowedasignificantdifferencebetweenthe2groups in the second and fourth
hour.Thereafter, the difference in pain scores in both Ketorolac group and Tramadol group
were not significant.
Conclusion: We conclude that both Ketorolac and Tramadol offer equal post-operative
analgesia while Ketorolac had lesser side effects when compared to Tramadol.

A comparative study of tramadol versus ketorolac in pain management following third molar surgery

Dr. DeepaliJagdish Birla; DrPrashant Shriram; Dr. Hemant gadge; Dr.Priyanka Satpute; Dr.Nilesh Patil; Dr.Vaibhav Jain

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5269-5273

Background: The present study was conducted to compare tramadol versus ketorolac in pain management following third molar surgery.
Materials & Methods: 56 cases of impacted mandibular third molar were divided into 2 groups of 28 each. Group I patients were given tramadol 50 mg intravenously before the surgery and group II patients were given ketorolac 30 mg intravenously before the surgery.
Results: The amount of local anesthetic used was 5.8 in group I and 5.2 in group II, mean operating time was 18.2 minutes in group I and 17.1 minutes in group II, mean VAS was 21.0 mm in group I and 15.4 mm in group II, total analgesic consumption was 6.5 tablets in group I and 4.2 tablets in group II and mean global assessment scores was 2.7 in group I and 3.4 in group II. The difference was significant (P< 0.05).
Conclusion: Tramadol is a suitable and safe analgesic for the relief of post-extraction pain following mandibular third molar extraction surgery as compared to Ketorolac.