European Journal of Molecular & Clinical Medicine

Schwannoma is also known as a neurinoma or neurilemoma. Schwann cells, which provide the insulating layer around the peripheral nerves, cause this specific type of nerve sheath tumour to develop. They may spread to nerve roots or nearby peripheral nerves. A Twenty-nine years old male presented to the OPD of general surgery with an asymptomatic retroperitoneal mass that was found during a regular medical check-up and imaging studies. Patient had given complaints of right lower abdominal pain 3 months ago which was initially judged as subacute appendicitis. No complaints of nausea/vomitings. No bowel/bladder complaints. Investigations revealed the presence of an enhancing solid mass lesion in right iliac region inferior to the caecum, most likely a benign neurogenic spindle cell tumor/ mesenchymal tumour arising from lateral femoral cutaneous nerve of thigh. He underwent successful Laparoscopic resection of retroperitoneal schwannoma with appendicectomy.

Coronary artery disease (CAD) is more common in diabetics and is the leading cause of death in patients with type 2 diabetes and is often asymptomatic because of silent myocardial ischemia. It has been recognized for several decades that diabetes mellitus is an established risk factor for cardiovascular morbidity and mortality. About three-quarters of the cardiovascular deaths from diabetes result from coronary artery disease. Coronary artery disease is multifactorial in etiology and has several important risk factors, out of which diabetes is one of the important modifiable risk factor. The patients of type 2 diabetes mellitus without clinical evidence of coronary artery disease attending diabetic clinic, cardiology and medicine OPD, at medical college and hospital were enrolled in the present study. In the present study out of 102 patients, TMT was positive in 32 (31.37%) and negative in 70 (68.63%) patients. TMT was positive in 13/61 (21.31%), 9/27 (33.33%), 7/10 (70%) and 3/4 (75%) patients with duration of diabetes >5, 6 to 10, 1 1 to 15 and 16 to 20 years respectively.

Aim: To study symptomatic and asymptomatic urinary tract infections in patients with diabetes mellitus.
Materials and Methods: The current prospective observational research was carried out on one hundred patients with confirmed diagnoses of diabetes mellitus admitted to the Medicine Dr DY Patil Medical College Hospital and Research Centre in Pimpri, Pune, from October 2020 and September 2023. After receiving approval from the institutional ethics committee, the research was carried out. Every patient had a thorough physical examination and complete history taking in accordance with the proforma. All of the collected information was input into a spreadsheet (Microsoft Excel 2010) and then transferred to the data editor in SPSS 20. (SPSS Inc., Chicago, Illinois, USA).
Results: The prevalence of symptomatic UTI in the study population was 34% and asymptomatic UTI was found prevalent in 66% of the study subjects. The average age of the subjects with symptomatic UTI was 46.32 years and asymptomatic UTI was 52.16 years. Majority of the subjects in both the groups showed HbA1c levels ≥7 (69%) and rest (31%) showed levels below 7. Bacterial culture report showed that E. Coli was found more prevalent in both groups (52%) followed by K. Pneumoniae (14%), Pseudomonas (3%), Coagulase Negative Staphylococcus (2%), Enterococcus Spp. (2%) and P. Rettgeri (1%).
Conclusion: The study indicated that the presence of prior urinary tract infections and inadequate Glycemic control were significant contributors to the high prevalence of urinary tract infections among the study population.

Introduction: Asymptomatic bladder infection that is detected by a positive urine culture is also common among diabetes mellitus patient which progress to symptomatic infection and subsequent complication. Therefore, it becomes essential to screen urinary tract infection in diabetes mellitus patient so that its progress to complication can be prevented. Hence present study has been designated to know the prevalence of asymptomatic bacteriuria among females affected with diabetes mellitus.

Latest proof shows that in humans, SARS-CoV-2 proliferates and fades symptomatic or asymptomatic infected individuals, the etioloidal agent that induces COVID-19. Subsequently, SARS-CoV-2 can be discharged and even opened through wastewater and sanitation systems on site. SARS-CoV-2 can be spread by the inhalation of polluted aerosols and goutlets in waste water plumbing systems in particular in heavily inhabited suburban areas in the case of faeces, waste water or wastewater systems on-site. Potential faecal-oral transfer has also been proposed along the human gut-wastewater diet spectrum. The detection in the human gastrointestinal tract, faeces, and untreated wastewater of SARS-CoV-2 RNA suggests probable COVID-19 faecal-oral transmission 1–4. A second line of recent evidence is extracted from a series of experiments focused on an overview of shelled disease, indicating SARS - COV-2 is prone to facal oral transmission and has a rigid shell and low shell disorder. The transmission path between faecal and oral has also gained substantial interest lately as an alternate transmission pathway but there is still no epidemiological data to support this theory. There could be a fast propagation of the pandemic via several COVID-19 transmission pathways.

Metaphyseal dysplasia (Pyle's disease) is rare autosomal recessive disease. Only few cases were reported around the world since 1930 when Edwin Pyle, an orthopedic surgeon from United States, first describes the disease. Pyle's disease is asymptomatic; it may be diagnosed incidentally during routine radiological examination for a genu valgus deformity. From orthopedic point of view, Pyle's disease requires no treatment except for deformity correction or management of fractures. Orthodontic intervention may be required for malocclusion and abnormal dentation.