Keywords : Blood components
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 11, Pages 3631-3636
Background:Packed Red blood cells (PRBCs) can be preservedunder optimum conditions at 2-60 C in specialised blood storage refrigeratorsfor about 42 days and are needed for various life-saving blood transfusions, but during this shelf lifethey undergo continuous degradation. RBCs go througha variety of changes due to storage that affecthealth of RBCmembrane and oxygen delivering capacity, whichcan have outcomes which are clinically unwanted. These adverse variationsare collectively referred to as ‘storage lesions’ and because of these changes the lifespan of stored RBCs is limited during which they offer clinical benefits. It is for this reason the optimum duration of storage warrants routine evaluation and careful consideration. The main objective of this study is to assess internal quality control of packed red cells through its shelf life as an indicator of our blood centre quality and storage efficacy of Blood component PRBC. Aim and Objectives-
To assess storage effects on Blood Component - PRBC in JNMC Blood Bank, Sawangi Meghe Wardha.
To test RBC count, Haemoglobin and RBC indices of PRBC at day1, day 21 and day 42 post collection in JNMC, Blood Bank
To compare the parameters of RBC count, Haemoglobin and red cell indices and assess the changes due to storage on day1, day 21 and day 42 post collection in JNMC, Blood Bank.
Methodology: This study is a prospective Cohort type, Total of 50 PRBC bags will be analysed for RBC count, Haemoglobin and RBC indices with on Day 1, Day 21 and Day 42 post collection. The data collected will be tabulated and various statistical tools will be applied.
Expected Results: conclusion of effects of storage will be drawn from the analysis of study parameters on the predefined days of analysis in packed red blood cells.