Online ISSN: 2515-8260

Keywords : Respiratory distress

Evaluation of Spectrum of Pulmonary Diseases Among Hospitalised Patients of the Respiratory Intensive Care Unit at a Tertiary Care Centre

Gaurav Sahu, Bhupendra Kumar Rajak, Rajdeep Dhandhukiya

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 3440-3443

Introduction: Respiratory diseases are reportedly the major forefront runner in causing the morbidity and mortality globally thus imposing great global health burden. , the present study was undertaken to assess the spectrum of pulmonary disease affecting the persons admitted to respiratory intensive care unit.
Materials and Methodology: For the study purpose, 120 subjects with various respiratory illnesses who were admitted in RICU were included. A written informed consent was obtained from all the study participants after briefly explaining the study protocols to the study subjects. Complete demographic detail for each of the study participants that include past medical and surgical history, family history, as well as history of present illness. The statistical analysis of the data was done using SPSS version 11.0 for windows.
Results: The age of participating patients ranged between 32 to 72 years. The number of male subjects was 76 and number of female subjects was 44. The lowest number of patients were seen with Bronchiectasis (n=8). The results on comparing were found to be statistically non-significant. (p>0.05)
Conclusion: This study provided enough support to show that bronchial asthma, pulmonary tuberculosis, COPD are considered to the most common and frequent nosocomial infections among those patients admitted in RICU. But future research are needed to be carried forward the study in a nurturing manner for the betterment

Clinical study of etiology & immediate outcome of acute poisoning in children at a tertiary hospital

Nishad Yashawant Patil, Rajendrakumar Hiralal Bedmutha

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 4066-4071

Background: Respiratory distress (RD) is a challenging problem and is one of the most common causes of admission in neonatal intensive care unit (NICU). The common causes of RD in neonates includes transient tachypnea of the newborn (TTN), hyaline membrane disease (HMD), birth asphyxia, pneumonia, meconium aspiration syndrome (MAS), and other miscellaneous causes.Present study was aimed to clinical profile of neonates admitted in NICU with respiratory distress in a tertiary care hospital.
Material and Methods: This study was prospective, observational study, conducted in neonates admitted to NICU with respiratory distress.
Results: In present study, majority neonates were male (56.38 %), had birth weight 1.5 – 2.5 kg (46.28 %), were term gestational age (41.49 %) & delivered vaginally (52.13 %). Symptoms and signs of respiratory distress noted were tachypnea (86.17 %), flaring of alae nasi (84.04 %), chest in drawing (82.45 %), grunting (47.34 %) & cyanosis (42.55 %). Premature rupture of membranes (13.83 %), meconium‑stained amniotic fluid (11.17 %), hypertension (9.04 %), maternal pyrexia (5.85 %), foul smelling liquor (2.66 %) & diabetes mellitus (2.13 %) were maternal risk factors observed among neonates with respiratory distress. Among neonates admitted with respiratory distress common diagnosis were transient tachypnea of newborn (34.57 %), sepsis (20.74 %), respiratory distress syndrome (11.17 %), meconium aspiration syndrome (9.04 %), hyaline membrane disease (8.51 %) & birth asphyxia (5.85 %). Majority neonates were discharged uneventfully (86.71 %) & mortality was observed among 16 neonates (8.51 %).
Conclusion: Common diagnosis observed in neonates with respiratory distress were transient tachypnea of newborn, sepsis, respiratory distress syndrome, meconium aspiration syndrome, hyaline membrane disease & birth asphyxia.


Dr Abhinaya Chengala,Dr M. Balasaraswathi, Dr V Suvarna, Dr B Aparna

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 6, Pages 263-275

Aims: The aim of my study is to evaluate the maternal and perinatal outcomes in pregnant women with Sickle cell anemia and Thalassemia.
Material and methods: The present study was undertaken in Mamata General Hospital with an aim to know the occurrence of sickle cell anemia and thalassemia in antenatal women and to evaluate the maternal and perinatal outcome.
Results: Out of the 30 women considered for the study, 20 had sickle cell disease and 10 had thalassemia. Most common age group was between 21-25years of age in both groups of women with 85% and 50% in each respectively. Mean age is 23±2years. Contracted pelvis was the indication in 17% in SCD. However abnormal color doppler study was the indication in 8% of SCD women and 17% in women with thalassemia. Maternal request and abruption were the indications in 8% each in SCD group. The need for transfusion was seen in about 45% of the SCD women and in 30% of the women with thalassemia. The incidence of Low birth weight of <2.5kg was among the most probable cause for neonatal morbidity in 40% of the neonates born under in each group with SCD and thalassemia.  There was 5% intrauterine fetal death and another 5% of the women had intrauterine growth retarded babies.  In thalassemia the most common fetal complications were neonatal jaundice in 30%, low birth weight in 20% and respiratory distress in 20% respectively.  The perinatal outcome in the 20 neonates born to women with SCD, 80% neonates were alive, intrauterine death was seen in 5% and neonatal deaths were 15%. Whereas in 10 neonates born to thalassemia women 70% of the neonates were alive and 30% neonatal deaths were recorded. Among the study group, the most preferred mode of family planning for the women with SCD in the present study was permanent sterilization in 50%. Next most preferred modality was injectable (DMPA) in 45%, and remaining 5% opted for barrier method of contraception.
Conclusion:   The obstetric outcome in women with Sickle-cell disease showed significant maternal morbidity. However though low in prevalence, the obstetric outcome in the group of women with thalassemia had low incidence of complications when compared to pregnancies with SCD. However both the groups were prone to neonatal morbidity and mortality.

Tracheostomy on a COVID-19 Patient:Case report and Review of Literature

Nekwu E. Okolugbo; Ufuoma M. Efole; Onome O. Ogueh; Anastacia O. Ojimba; Ejiro A. Benjamin

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 2864-2872

A new respiratory illness the severe acute respiratory virus (Sars Cov2), was identified at the beginning of the new decade 2020.
Severe cases present with respiratory distress and tracheostomy has been considered to play a role in their management.
We present a report of a Tracheostomy performed on a Covid-19 patient and also a review of the relevant literature.
A 62 year old man, was brought in on a transport ventilator with a endotracheal tube insitu. From a private clinic after testing positive for COVID-19.
While on admission he desaturated further and subsequently had a tracheostomy done with marked improvement of the oxygen saturation immediate post operative period.
However on the day following the tracheostomy, he desaturated suddenly, resuscitation was commenced immediately but proved abortive, Patient was later certified dead.
Despite the unfavourable outcome, we believe the decision to perform the tracheostomy offered the patient a chance at survival