Online ISSN: 2515-8260

Keywords : Allergic Rhinitis

Comparative Study Ofpoly Herbal Tabletalong With Healthy Diet And Lifestyle In Children with pratishyay (Allergic Rhinitis)

Amit Gulhane; Renu Rathi; Bharat Rathi

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 3382-3392

Pratishyay(Allergic Rhinitis)has been described in various classics of Ayurveda as an independent disease and as a symptom or complication of other diseases. Due to the similarities between the clinical picture, allergic Rhinitis which is one of the most frequentsymptoms in pediatric age group and common reason for which parents look for medical care for their childhas been considered underPratishyaya. The present trial was aimed at studying the comparative efficacy of a poly herbal tablet named as TrayushnadiVatiwith Pathya(diet and life style modifications)as per classical reference of Ayurvedahave elaborated their role of Pathyain the managementof Pratishyaya.
The present study was a comparative parallel group single centre fixed dose interventional study in which total 33 subjects were enrolled as per the inclusion criteria. The trial drug was administered for a period of 7 days during which assessment of both subjective and objective parameters and other observations were recorded on 0th,3rd and 7thday but hematological parameters were performed only before and after the trial. Follow up was for a period of 14 days post trial.The subjective parameters were graded as per their intensity. The level of significance of the efficacy was determined by using the obtained data which were analyzed statistically with Wilcoxon Signed Rank and Paired t tests. P value of < 0.05 was considered as statistically significant.It was observedin the study that school going age group was more likely to suffer from Pratishyay. There was significant improvement in all subjective criteria whereas significant changes were noted in Nasal Discharge and total leukocyte count. The trial drug was well tolerated by the subjects and no adverse drug reaction was reported during or after the trial. The study revealed a good efficacy of TrayushnadiVati in breaking the pathogenesis of Pratishyay. However, as it was conductedin limited samples, further large sample studies would be more preferable.