Online ISSN: 2515-8260

Keywords : imaging

Magnetic resonance venography evaluation in cerebral venous thrombosis – A retrospective stu

Dr Nipa Hathila, Dr Harish Chandra Chaturvedi, Dr. Shekhar Karnawat, Dr. Shrinidhi Kulkarni, Dr. Kanaram Yadav

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1418-1424

Introduction: Cerebral venous thrombosis is a relatively uncommon disorder which has
an estimated annual incidence between two to seven cases per million in the general
population. 1 The incidence was likely underestimated before the advent of prompt noninvasive
imaging methods. It is estimated that five to eight cases per year might be seen
at a referral centre. Cerebral venous thrombosis or occlusion by extrinsic compression
that eventually progresses to a complete occlusion is an elusive diagnosis because of its
non-specific presentation and its numerous predisposing causes which can precipitate
the condition. It often affects young and middle-aged patients which more commonly
involved in women. It is an uncommon cause of cerebral infarction relative to arterial
disease which is an important consideration because of its potential morbidity. The
imaging characteristics of CVT that can be observed through MRI include: (1) brain
parenchymal imaging that appears in the form of non-specific lesions, such as
intracerebral hemorrhages or infarcts, edema, isolated or associated with infarcts or
hemorrhages, and it can even be considered normal in about 30% of patients.9 MRV
features include non-visualization of the arterial & venous vessels (i.e., no flow), flow
defect and presence of collaterals at the site of occlusion.

The profusion of breast lesions in breast biopsies showed imaging and pathological discordance

1Amod Kumar, 2Aashish Gupta, 3Monica, 4Payal Kumari, .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 3286-3293

Introduction: For nonpalpable breast lesions, imaging-guided breast tissue biopsy has become a viable alternative to open surgical biopsy. It can be difficult to talk about abnormal results of the connection between imaging and pathology findings because they can help with decision-making about additional treatment options by arriving at a full diagnosis.
Materials and Methods: This was a retrospective study. A specialist radiologist collected and classified radiological data from 500 patients' imaging-guided breast biopsies over a 6-year period using the BIRADS format. The discordance between histopathology reports was investigated.
Results: A total of 500 cases were reviewed. Approximately 4.6% (23) of cases fell into BIRADS 2 category, 33.6% (168) of cases fell into the BIRADS 3 category, 24.4% (122) into the BIRADS 4, 36.6% (183) into BIRADS 5 categories and 0.8% (4) into BIRADS 6 categories. Approximately 49.2% (n = 246) cases were benign, 3.4% (17) belonged to the high‑risk category, and 47.4% (237) were malignant. The number of discordant cases was 12 (2.4%), mostly due to technical factors. The sensitivity of biopsies to detect malignancy was 85%, specificity was 96%, and accuracy of biopsy in diagnosing cancer was 90%.
Discussion: The most sensitive way for detecting early breast cancer is the "triple assessment." Because of the high occurrence of carcinoma in these lesions, an effective communication line between a physician, radiologist, and pathologist is required for surgical excision in discordance.
Conclusion: In discordant cases, the ultimate choice is based on two concordant findings out of the three parameters, either due to abnormal imaging results or abnormal pathology findings. A multidisciplinary breast conference is held, with the pathologist taking an active role.