Online ISSN: 2515-8260

Keywords : Gallstone


Dr Ramaswami B,Dr Natarajkumar, Dr Rakesh Shaganti

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 331-335

To study the incident of gallstone stone in different age and sex.
Cross-sectional observational study,
Place and duration of study:
Mamata Medical College and General Hospital, Khammam from October 2018 to September 2020.
RESULTS: In the present study, among 50 cases, 41 (82%) were females and 9 (18%) were males
with male to female ratio of 1:4.5. Representing the majority of the study population were females.
Out of these 3 cases two were pigmented, one was cholesterol stone. But Chi-square statistic at 0.866
with P value of 0.64. Out of 41 female patients in the present study, 10 had a history of OCP use at
some point in their life. Among them 5, 4, 1 patients had pigment, cholesterol and mixed stones.
Mean serum bilirubin value was more among pigmented stone group (1.069 mg/dl) as compared to
mixed (0.850 mg/dl) and cholesterol group (0.6 mg/dl). Mean serum cholesterol group (3.382 mg/dl).
CONCLUSION: On the basis of the above observations, it is possible to say that pigment gallstone
patients have high serum bilirubin, calcium and phosphate levels and the type of gallstone doesn’t
depend on age, sex, BMI status and OCP usage.

Using Fourier Transform Infrared and chemical Analysis for differential between Gallbladder stone diseases

Antesar Rheem Obead

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4342-4349

Background:- the aim of the present study was to evaluate component of variety color of gallstone samples using Fourier Transform Infrared Spectroscopic Technique (FTIR) , also study the cost and simple method of Fourier Transform Infrared Spectroscopic Technique (FTIR) compare with result of quantitative chemical analysis like total cholesterol, calcium , total bilirubin , total protein . Material and method:- the material in the study were gallstones removed from 140 patient ( 94 female, 46 male) after surgical. All samples were stored in sterile dried counter and used for FTIR spectral analysis and quantitative chemical analysis. Result :-the results of FTIR were suggested that cholesterol and mixed gallstones content were a major component , cholesterol gallstones were characterized by the band 2949,1456,1053 cm -1 , while in mixed stones the band of cholesterol between 2800-3000 cm1 due to asymmetrical stretch vibration of CH2 and CH3group, and quantitative chemical analysis were explained the cholesterol stones and mixed stones were higher cholesterol compared to pigmented stones which were richer in total bilirubin and total protein. Conclusion:-the investigation were suggested thatFourier Transform Infrared Spectroscopic Technique (FTIR) is the less cost and simple method to find component of differential gallstone samples and this method conformed the cholesterol and mixed with calcium carbonate , bilirubin and total protein is the major component of human gallstones from Babylon,Iraq.