Online ISSN: 2515-8260

Keywords : biopsy


Pardaev Saidkasim Narkulovich; Narkulov Maksudzhon Saidkasimovich; Meliboev Salim Tashtanovich; Khasanov Aziz Batirovich

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 2304-2310

Infectious spondylitis accounts for 4 - 8% among suppurative diseases of the musculoskeletal system, and its frequency is estimated at 1.0 - 2.5 cases per 100,000 population. A special form of spondylodiscitis - acute post-manipulation spondylodiscitis - is observed in one of 40-50 patients who underwent discectomy from the posterior approach for a herniated disc, which, given that this operation is the most frequent in neurosurgery, allows one to assess the total volume of the problem.

Evaluation of Spectrum of Neck Masses on MDCT and Tissue Diagnosis Correlation

Shaina Kaur; Anisha Galhotra; Arnav Galhotra; Ritu Dhawan; Kamini Gupta; Parambir Sandhu; Kavita Saggar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 8316-8327

INTRODUCTION: The neck is a part of the body that has many vital structures in a relatively small region with complex anatomy. Various pathologies of the neck may present as neck swellings. The mass may be first noticed by the patient, other individual or by the physician as an incidental finding during physical examination. With the improvement of CT imaging techniques, shorter examination time, higher resolution imaging, Multidetector CT is particularly useful in evaluation of neck masses. AIM OF STUDY: To assess the role of MDCT in neck masses for characterization of nature of lesion (benign or malignant) and organ of origin and to Correlate with tissue diagnosis wherever possible. MATERIALS AND METHODS: Patients presenting with clinical suspicion of neck masses and referred for MDCT neck to the Department of Radio-diagnosis and Imaging, DMCH, Ludhiana were included in this study. RESULTS: 18.9% patients were in 31-40 years age group. Mean age for malignant lesions was 58.3 years. Most common space involved was visceral space (48.9%) and the most common diagnosis was benign thyroid nodule(s) (30%). Many of malignant lesions showed ill-defined margins (68.18%), necrosis (62.5%), heterogeneous enhancement (68.2%), bony infiltration (20.8%), obliteration of fat planes (8.3%), metastasis (45.8%), involvement of adjacent neck spaces (37.5%), vascular involvement in form of internal jugular vein thrombosis (8.3%) of cases. In diagnosing malignant lesions, CT had a sensitivity of 95.83%, specificity of 96.30%, positive predictive value of 92.00%, negative predictive value of 98.11% and accuracy of 96.15%. CONCLUSION: MDCT has high accuracy for characterization of a lesion as benign or malignant. It provides the best possible contrast of soft tissue (with the choice of appropriate delay, contrast agent volume, flow rate and scanning time), visualization of vascular structures, extent of lesion, bone and airway details, thus helps in making diagnosis and deciding further course of management.

Study of nontuberculous mycobacterial diseases diagnosed by rapid immunochromatotography method

Jeppu udayalaxmi; Ganesh Arjun

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 10, Pages 1622-1630

Background: Most laboratories do not have facilities for identification of mycobacteria to species level. BD MGIT TBc immunochromatographic strip differentiates mycobacteria grown in liquid media as MTC or NTM. In the present study we clinically correlate NTM identified by above method. Methods: Culture was done by BD BACTEC TMMGIT 960. All positive cultures were subjected to a BD MGIT TBc immunochromatographic strip method for differentiating MTC and NTM. Results: Of the 29 cases of suspected NTM there was a single case of UTI, a case of right frontal lobe abscess, a case of synovitis, a case of post hernioplasty infected mesh and 25 patients were having respiratory symptoms. All patients responded well to antibiotic therapy which included ATT, fluoroquinolones, cephalosporins, azithromycin, clarithromycin singly or in combination. Conclusions: Diagnosis of NTM done with BD MGIT TBc immunochromatographic card test was found to useful in the absence of a definitive species identification.