European Journal of Molecular & Clinical Medicine

As stated by Hippocrates - “Divine is the task to relieve pain”
Relief of pain during surgery is one of the components of balanced anaesthesia but this pain relief should be extended to the postoperative period also. According to Perkins and co-workers poorly managed acute pain like postoperative pain can lead to the occurrence of chronic pain.
Materials and Method: This clinical study was conducted on 156 adult patients of ASA physical status I to III in the age group of 18-60 years of either sex posted for elective lower abdominal or lower limb surgeries under spinal anaesthesia after taking informed consent at a tertiary hospital Vijayapur.
Results: Statistical tests used: anova, chi square test and tukey test.
Discussion: Spinal anaesthesia is currently wide spread popular anaesthetic technique available today. It has the definitive advantage that profound nerve block can be produced in a large part of the body by the relatively simple injection of a small amount of local anaesthetic.
Conclusion: Acute pain following surgical procedures is unique to the clinical practice of pain medicine. It is one of the few opportunities in which the cause of pain is known before its occurrence, the pain is reliably expected to occur and can be annulled effectively

Introduction: The term "abortion" refers to the natural or artificial termination of a pregnancy prior to foetus viability. The second trimester, which is divided again into early and late periods, lasts from 13 to 28 weeks of gestation. Because of foetal abnormalities such as chromosomal aneuploidy, structural defects, and oligohydramnios discovered by antenatal screening programmes, many second trimester abortions are medically induced (resulting in intrauterine foetal demise). The combination of antiprogestin (mifepristone) and PGE1 analogue Misoprostol seems to be the most effective medical technique for ending a pregnancy in the second trimester.
Aims and Objectives: To evaluate the safety and effectiveness of two medical procedures for an abortion in the second trimester: preinduction with mifepristone followed by a misoprostol regimen (group 1), and preinduction with a foley cather followed by a misoprostol regimen (group 2). (Group 2). In order to make a comparison between the length of time that passed between the induction and the abortion in both groups, we will compare the length of time that passed. In order to provide an accurate assessment of the disparity in abortion rates between the two populations:
Methods: This study is a prospective randomized trial involving sixty healthy women who chose to have their pregnancies terminated at a tertiary care center's Department of Obstetrics and Gynecology. The women's ultrasounds confirmed an intrauterine gestational age ranging from thirteen to twenty-six weeks of pregnancy.
Results and discussion: Group 1's average induction abortion time was 8.93 hours, whereas group 2's was 8.75. None was statistically significant. 42 women who used mifepristone and misoprostol had IAIs under 6 hours, according to Bijeta et al. The average IAI for Mifepristone + Misoprostol was 8.6 hours and 15.5 hours for Misoprostol. Hourly comparison of mifepristone-misoprostol induction abortion studies: Neha Agarwal et al. found a 6-hour IAI. Sin Eh Goh et al. found a 6.7-hour average IAI. Kulakarni Kranti's average IAI was 8.15 hours. Tang et al. found a 10.5-hour IAI. Ashok et al. found a 6.25-hour IAI. In Subha et altrial, the foley catheter termination group received misoprostol after 13.84 5.37 hours.
Conclusion: Both the mifepristone preinduction with misoprostol and the foley catheter preinduction with misoprostol procedures are risk-free and simple ways for terminating a pregnancy in the second trimester. There was no statistically significant difference between the two groups in terms of the mean induction-abortion interval, the mean doses of misoprostol required, the side-effect profile, or the rate of women who experienced a complete abortion. In the group that used mifepristone and misoprostol, the success rate was 100%, while in the group that used foley bulb induction, the success rate was 96.7%. In this particular trial, the group that received mifepristone and misoprostol had a significantly lower level of pain intensity and a shorter length of time spent in the hospital. This difference was statistically significant. Therefore, it is possible to utilise either of these approaches to stop a pregnancy in the second trimester, although this will rely on whether or not mifepristone is readily available.

Background: In the course of any living thing's existence, ageing is a normal and expected component of the process of development. There is very nothing that can be done to slow down the ageing process, as it is a natural part of life. It is not merely a biological phenomenon, but also has psychological and social ramifications for humans.

Background
Stapled hemorrhoidectomy has a number of advantages over excision hemorrhoidectomy, including less postoperative pain, a shorter stay in the hospital, and a faster recovery. Furthermore, stapled hemorrhoidectomy is linked to a reduced rate of hemorrhoidal recurrence during long-term follow-up.
Methods:
The study included 100 patients, 50 of whom received open and 50 of whom underwent stapled haemorrhoidectomy. Averages, standard deviation, unpaired student t test, Mann Whitney U test (for non-parametric skewed distribution), and Fischer exact test were used to assess significance levels. If the p-value ˂ 0.01 or 0.001, the difference is extremely significant. The difference is significant if the p-value ˂0.05.
Results
In terms of postoperative pain, operative time, and return to normal activities, the stapled method for haemorrhoids is preferable than the Milligan Morgan haemorrhoidectomy. It's simple and obvious to learn. Early functional and symptomatic results have been positive, and they appear to be comparable to or better than those obtained using conventional approaches. However, long-term assessment of these parameters is required.
Conclusion
I conclude that both treatments were effective for hemorrhoidectomy treatment, however Stapler hemorrhoidectomy had advantages in terms of shorter operative periods, less intra- and post-surgical bleeding, and a lower incidence of various post-operative sequelae. Patients with haemorrhoids frequently avoid surgery for fear of enduring excruciating pain after a haemorrhoidectomy.
 

A text classification is a well formed process using various measurable properties and computerized logical procedure to fetch a pattern from different classes.Since classification is important for the pattern recognition process, there are some issues with well-formed classification in this process, which is one of the important issues for proper development and improvement of productive data examinations. On behalf of the versatility of learning and the ability to deal with complex calculations, classifiers are consistently best suited for design patter recognition issues. The aim of this paper is to present a result based comparative study of different classifiers and the optimal recognition of results computation through the Devanagari Handwritten characters and numerical values. Different classifiers were used and evaluated in this investigation including k-Nearest Neighbor (k-NN), Support-Vector machine (SVM), Naïve Bayes, Decision Tree, Random Forest, and Convolution Neural Network (CNN). To accomplish the experiment purpose, this paper used an unbiased dataset with including 123 samples that consists of 123 characters and 123 numerical values. Python 3.0 with sciket learn machine learning open-source environment library have been used to evaluate the performance of the classifiers. The performances of the classifiers accessed by considering the different matrices including dataset volume with best split ratio among training, validation, and testing process, accuracy rate, Ture/False acceptance rate, True/False rejection rate and the area covered under the receiver operating characteristic curve. Similarly the paper shows the correlation of the accuracy of the experiments obtained by applying to chosen the classifier. On behalf of the exploratory results, the
infallible classifiers considered in this test have free rewards and must be executed in a hybrid manner to meet the thigh precision rates.In the views of test work, their result compressions and the examination to be performed, it is argued that the Random Forest classifier is performing in a way that the current use of the classifier to recognize the Devanagari Handwritten character and the numerical values with the accuracy rate 87.9% for the considered 123 samples.

The manufacturing companies are competing among themselves to be the leading manufacturer in the share market. With the rapid increasing competition in the market, the companies need to improve their operation by producing high-quality products, operated at the lowest possible cost. Thus, to achieve this target, the bottleneck problem which affects the idle time and efficiency in the assembly line needs to be investigated. Besides, it also affects the production rate of the assembly line and can have a huge impact on the increase in operational costs. Since there are various line balancing algorithms available as the solution for the bottleneck problem, it is crucial to determine which line balancing algorithm works the best for the associated assembly line. Therefore, this study aims to analyze and compare the two most frequently used line balancing algorithms, which are the Largest Candidate Rule (LCR) and Ranked Positional Weights (RPW) algorithm. The studied applied to three different industries, which are electronic, food and automotive industries. The analysis and comparison are achieved through findings from Microsoft Excel calculation and simulation in Delmia Quest. The study indicates the best line balancing algorithm for the line balancing problem by these two parameters which are the line balance efficiency, Eb and the balance delay, d. According to the findings of the study, the best line balancing algorithm is dependable on the case study to be solved.