Online ISSN: 2515-8260

Keywords : Sedation


Dr. PratikshaChitta, Dr.MrunaliniAlugolu, Dr Ramakrishna Shatagopam, Dr Bhanu Lakshmi, Dr Rekha Kone

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 5971-5981

Aim: The purpose of this study is to analyze and compare the properties of
Dexmedetomidine with that of Nalbuphine regarding duration of sedation, recovery and
adverse effects in short surgical procedures.
Materials and methods: It is observational clinical study involving 60 patients belonging to
ASA grade 1 & 2 posted for elective minor surgical procedures lasting about 45 -60 minutes,
comparison between Dexmedetomidine and Nalbuphine was done and the onset of sedation,
duration of sedation and recovery from sedation including adverse effects of both drugs,
hemodynamic and respiratory parameters were evaluated. Patients were randomly divided
into 2 groups of 30 each .Group N( Nalbuphine) received 50 mcg /kg of Nalbuphine and
Group D(Dexmedetomidine) received 1 mcg/kg of Dexmedetomidine over 10 minutes .
Results: Demographic parameters in both groups were comparable (p>0.05).Nalbuphine and
Dexmedetomidine has comparable onset of time for sedation, duration of sedation and
recovery from the sedation. Onset of sedation is fast in Dexmedetomidine; total duration of
sedation is more with dexmedetomidine and has provided good sedation during the surgical
procedure. As reported in several studies dexmedetomidine offered good cardiovascular
stability without the risk of hypotension . No significant side effects were noted with
dexmedetomidine when compared with Nalbuphine.
Conclusions:Dexmedetomidine when used as a peri operative sedative agent has faster onset
of sedation ,longer duration of sedation ,and the recovery from sedation

Case Preferences In Choosing Consious Sedation Versus General Anesthesia Amongst Pediatric Dentists: A Research Survey

Dr. Sravanthi Veeramachaneni; Dr. Sandeep Dande; Dr. Tulluru Ajay Mohan; Dr. Mohammed Muzammil Khan; Dr. DilipKumar. S; Dr Shilpi Verma; Dr. Priyanka Parhad

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 1, Pages 1252-1257

Aim: Purpose of our research was to assess the preference of pediatric dentists to carry out
treatment with either conscious sedation or with general anesthesia.
Methodology: 50 children were selected for your study who did not have any previous
medical conditions. Patients requiring complete dental treatment were treated under GA,
those requiring one or two procedures were under conscious sedation. The two groups of
patients were evaluated in terms of vital signs, duration of the treatment procedure, patient
behavior, recovery time and comfort experienced by the dentists and the anesthesiologists.
Results: Dentists in sedation group were anxious, uncomfortable and restless during
implementation of dental treatment. During dental procedure under sedation, some
interruption has been noted in few cases such as vomiting during the procedure (3 cases).
Those who vomited, during the procedure, their heads were turned to one side, the
procedure was discontinued immediately (to prevent aspiration), and the patients were
referred for treatment under GA.
Conclusion: Dental treatment under CS can be successful with little or no complications if
the cases are well selected by qualified trained dentist.