Online ISSN: 2515-8260

Keywords : surgery

Systematic Review And Meta-Analysis: Risk Factors Of Acute Kidney Injury In Major Abdominal Surgery

Emminarty .; Hasyim Kasim; Haerani Rasyid; Syakib Bakri; Andi Makbul Aman; Husaini Umar; Muh. Ilyas; Arifin Seweng; Gita vita soraya

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 944-952

Background and objective: Acute kidney injury (AKI) is a common complication in patients undergoing major abdominal surgery. Various recent studies reported an incidence of AKI after surgery ranging from 6.7 to 32%. Risk factors for AKI in this setting may be procedure-related factors, post-operative complications and several patient-related include age, gender, comorbid disease Diabetes Melitus (DM), Hypertension (HT), Cardiovascular disease (CVD), and physical status. This study aimed to explore the risk factors of AKI in major abdominal surgery
Methods: We conducted a systematic literature search from PubMed and Cochrane Library. We included articles describing AKI in the setting of major abdominal surgery, published from 2015 until now, and cohort study design. This review was registered with PROSPERO (CRD42020216405)
Results: From 478 articles, 4 articles met our inclusion criteria describing AKI outcomes in varied population 683-3751. Prevalence of AKI 8,8 %. Age patient risk AKI in major abdominal surgery with Mean difference was 3.04 (95% CI = 1.83-4.25; P <0.00001). Meta-analysis of the four studies showed that Male had a pooled Odds ratio (OR) of 1.79 (95% CI = 1.04-3.08; P = 0.04) , DM OR 1.64 (95% CI 1.36-2.03; P <0.00001), HT pooled OR 1.90 (95% CI = 1.30-2.78; P = 0.0009), CVD has an OR of 1.58 (95% CI = 0.91-2.75; P = 0.10), physical status ASA≥ 3 (The American Society of Anesthesiologists) score has pooled OR 1.70 (95% CI = 1.16-2.49; P = 0.007)
Conclusion: Risk factors of AKI in major abdominal surgery setting are higher significantly in male, and patient with comorbid disease DM and HT had a significantly high risk of AKI, as well as physical status score ASA > 3.


M.Pauline Nivetha

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 6018-6020

The term “gossypiboma” is derived from the latin word “gossypium” cotton wool or cotton and the suffix “oma” meaning a tumor or growth and describe a collection within a patients’s body comprising a cotton matrix enclosed by a granuloma. A surgical instruments accidentally left inside the body during surgery is called a foreign body granuloma or a retainted foreign body. In many studies found that the majority common threat factors associated with “retained foreign bodies” are emergency operations, unexpected changes in operating procedures, and when operating on patients with “higher body-mass index.


S.Vaibava Keerthana; Dr. Thulasiram; Dr.M.S. Kannan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 4, Pages 1753-1756

Anterior open bite is one of the most difficult malocclusions to treat with its varied characterizations. Appropriate etiology should be identified for effective management of open bite. Anterior Open Bite can irrespectively occur in all kinds of malocclusion. Aesthetics, speech, mastication and tooth wear are some of the common concerns for the patients. Thorough apprehension of the anomaly is important in determining the appropriate corrective measures. This review will throw more light on the etiology of open bite, diagnosis and treatment enabling the clinicians for better understanding of the malocclusion.


Dr. Anand V; Dr.Monisha S

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5745-5751

It is important, considering the wide range of orthodontic devices currently available on the market, to select the most biocompatible orthodontic implant available on the market. Current science data have shown that in vitro measurements of the toxicity of residual particles produced by various orthodontic apparatuses with oral cell lines provide accurate data. In this relation, three commercially available implants, i.e., stainless steel and titanium implants have been tested for in vitro biocompatibility. Methods: Human gingival fibroblasts (HGFs) have been used as the in vitro model to determine cellular morphology, viability of the cells, and cytotoxicity via a 24-hour and 72-hour test for celular implant exposure with 3-(4,5-dimethythiazol-2-yl)-, 2-5,5-diphenyltetrazolium bromide (MT) and LDH test. Results: The results compare implant surface structure and topography with biological, laboratory assessments related to the direct cells (genetic fibroblasts) and blood vessel toxicology (HET-CAM) trial. A relative cytototoxicity of HGF cells occurs for the stainless steel implant, while the other two tests did not produce substantial alteration in HGF cells. Conclusion: The stainless steel implant caused mild cytotoxic effects among the three orthodontic implants samples. This calls for improved alertness in their clinic usage, especially in patients with a strong sensitivity to nicke 1,2.