Online ISSN: 2515-8260

Keywords : type 2 DM


Anaemia and Its Associated Factors Among Type 2 Diabetes Mellitus Patients in Eastern India: A Cross Sectional Study

Shaibal Guha, Amit Kumar Das

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 5591-5598

Background: Anaemia is a common diabetes mellitus (DM) consequence that has a
negative impact on the progression and development of other diabetes-related
problems. Despite this, little is known about the prevalence of anaemia and its
associated variables in type 2 diabetes mellitus (T2DM) patients. As a result, the
purpose of this study was to look at the prevalence of anaemia and its associated
variables in T2DM patients.
Methods: A hospital-based cross-sectional study was carried out on 249 T2DM patients
who were chosen by a systematic random sample procedure. Face-to-face interviews,
anthropometric measurements, and laboratory testing such as haemoglobin
measurements, red blood indices, and serum creatinine analysis were used to collect
data. The data were coded and entered into Epi-data management version 4.4.1.0 before
being analysed using SPSS version 22. Bivariate and multivariate logistic regression
analysis were used to discover the determinants of anaemia. P-values less than 0.05 were
considered statistically significant.
Results: According to the findings of the study, 20.1 percent of the individuals were
anaemic. Age >60 years (AOR=3.06, 95 percent CI: 1.32–7.11), poor glycemic control
(AOR=2.95, 95 percent CI: 1.22–7.15), eGFR 60–89.9 mL/min/1.73m2 (AOR=2.91, 95
percent CI: 1.15–7.37), eGFR 10 years (AOR=2.75, 95 percent CI: 1.17–6.48), and
experiencing diabetic complications (AOR=3.81, 95% CI: 1.65–8.81) were significantly
associated with anaemia.

The Compatibility Of Hba1c And Glycated Albumin Levels As Markers For Blood Glucose Follow-Up In Type 2 Diabetes Mellitus

Edward Kurnia Setiawan Limijadi; Ivan Kurniawan Effendy

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 10, Pages 2312-2318

BACKGROUND: Diabetes mellitus (DM) is a group of metabolic diseases, characterized by hyperglycaemia that occurs due to abnormalities in insulin secretion. Uncontrolled diabetes will lead to the development of further complications. HbA1c level measurement is the current gold standard for monitoring glucose levels in DM patients. Glycated albumin (GA) is a fructosamine formed through a non-enzymatic glycation process. There are still few studies on the correlation between HbA1c and GA levels in T2DM patients. Therefore, we decided to investigate the correlation between HbA1c and GA levels in T2DM patients.
OBJECTIVE: To determine the correlation between HbA1c and GA levels in T2DM patients.
METHODS: This study was an observational study with a cross-sectional design conducted on 69 T2DM patients at Diponegoro National Hospital from June to August 2020. We collected data consisting of age, weight, blood pressure, waist circumference, HbA1c and GA levels. We measured HbA1c levels using I-chroma Boditech tool with the enzyme-linked fluorescent assay (ELFA) method, and GA levels using the Architect C8000 tool with an enzymatic method. Finally, we performed statistical analysis using Spearman's correlation test.
RESULTS: The median ± SE values of HbA1c and GA levels were (7.1 ± 0.19%) and (21.2 ± 0.85%), respectively. The Spearman's correlation test results between HbA1c and GA levels were p <0.001; r = 0.775.
DISCUSSION: Maintenance of blood glucose levels in the body is essential for T2DM patients. HbA1c and GA levels can be used for clinical evaluation of T2DM patients.
CONCLUSION: There was a strong significant correlation between HbA1c and GA levels in T2DM patients. HbA1c and GA levels can be used for clinical evaluation of DM patients according to the patient's condition.